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Association details:
| Biomarker: | EGFR E746_A750del |
|---|---|
| Cancer: | Lung Cancer |
| Drug: | Gilotrif (afatinib) (EGFR inhibitor, HER2 inhibitor, HER4 inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Case report: A case report and literature review about Pathological transformation of lung adenosquamous cell carcinoma
Published date:
10/18/2022
Excerpt:
A 55 year old female was diagnosed with lung cancer...Genetic test was EGFR-p E746_ A750del, T790M (-), and we replaced with the second-generation EGFR-TKI afatinib targeted therapy. Up to now, no recurrence or metastasis has been found.
DOI:
10.3389/fonc.2022.1029679
