Consistent with overall survival, patients who had a high EGFR gene copy number seemed to achieve better objective response rate and TTF than those with a low EGFR gene copy number (Table 3).....With gefitinib, longer median survival was seen in patients with a high versus low EGFR gene copy number (8.3 v 4.3 months, respectively; HR, 0.78; 95% CI, 0.54 to 1.13).