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Association details:
| Biomarker: | DDB1 overexpression |
|---|---|
| Cancer: | Multiple Myeloma |
| Drug: | lenalidomide (TNFα inhibitor, IL-6 inhibitor, IL-12 inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
EXPRESSION SIGNIFICANCE OF CRL4-CRBN PROTEINS COMPLEX IN MULTIPLE MYELOMA PATIENTS TREATED WITH IMMUNOMODULATORY DRUGS.
Published date:
05/14/2020
Excerpt:
The high DDB1 expression, as the only one, was associated with longer OS of MM patients treated with thalidomide or lenalidomide (p=0.002).
