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Association details:
Biomarker:CTAG1B antibody elevation
Cancer:Melanoma
Drug Class:Immunotherapy
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
New
Title:

Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients

Excerpt:
...melanoma-associated antibodies as predictive markers for CI therapy in two independent cohorts...In cohort 1, baseline levels of these antibodies were higher in the responder group, although statistical significance was only reached for NY-ESO-1 (p = 0.007)….Melanoma-associated antibodies may be candidate biomarkers for response and survival in metastatic melanoma patients being treated with CIs.
DOI:
10.1186/s40425-019-0523-2