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BIOMARKER:

CD74-ROS1 F2004L + PD-L1 expression

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Other names: PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule, CD74, CD74 Molecule, CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex Class II Antigen-Associated), CD74 Molecule Major Histocompatibility Complex Class II Invariant Chain, HLA Class II Histocompatibility Antigen Gamma Chain, HLA-DR Antigens-Associated Invariant Chain, Gamma Chain Of Class II Antigens, Ia-Associated Invariant Chain, MHC HLA-DR Gamma Chain, HLA-DR-Gamma, DHLAG, P33, Ia Antigen-Associated Invariant Chain, CD74 Antigen, Ia-GAMMA, HLADG, II, Ii, ROS1, ROS Proto-Oncogene 1 Receptor Tyrosine Kinase, V-Ros Avian UR2 Sarcoma Virus Oncogene Homolog 1, C-Ros Oncogene 1 Receptor Tyrosine Kinase, Proto-Oncogene Tyrosine-Protein Kinase ROS, Proto-Oncogene C-Ros-1, MCF3, ROS, V-Ros UR2 Sarcoma Virus Oncogene Homolog 1 (Avian), ROS Proto-Oncogene 1 Receptor Tyrosine Kinase, Transmembrane Tyrosine-Specific Protein Kinase, Receptor Tyrosine Kinase C-Ros Oncogene 1, C-Ros Receptor Tyrosine Kinase, Proto-oncogene C-Ros, C-Ros-1
Entrez ID:
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Trials
CD74-ROS1 F2004L + PD-L1 expression
LUAD
lorlatinib
Sensitive: C4 – Case Studies
CD74-ROS1 F2004L + PD-L1 expression
LUAD
nivolumab
Resistant: C4 – Case Studies
CD74-ROS1 F2004L + PD-L1 expression
LUAD
ceritinib
Resistant: C4 – Case Studies