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Association details:
Biomarker:
CD52 expression
Cancer:
Prolymphocytic Leukemia
Drug:
Campath (alemtuzumab)
(
CD52 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
Source:
NCCN
Published date:
01/05/2023
Excerpt:
T-Cell Prolymphocytic Leukemia….Retreatment with alemtuzumab (IV) ± pentostatin (if CD52 expression is still positive and relapse after a period of remission following first-line therapy).
Secondary therapy:
pentostatin
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