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GENE:

CCL5 (Chemokine (C-C motif) ligand 5)

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PD-L1 overexpression + CCL5 overexpression	Esophageal Squamous Cell Carcinoma	PD-L1 overexpression + CCL5 overexpression	Esophageal Squamous Cell Carcinoma	Immunotherapy Sensitive: C3 – Early Trials Immunotherapy Sensitive : C3	Immunotherapy Sensitive: C3 – Early Trials Immunotherapy Sensitive : C3
CCL5 overexpression	Small Cell Lung Cancer	CCL5 overexpression	Small Cell Lung Cancer	olaparib Sensitive: C3 – Early Trials olaparib Sensitive : C3	olaparib Sensitive: C3 – Early Trials olaparib Sensitive : C3
CCL5 overexpression	Small Cell Lung Cancer	CCL5 overexpression	Small Cell Lung Cancer	durvalumab Sensitive: C3 – Early Trials durvalumab Sensitive : C3	durvalumab Sensitive: C3 – Early Trials durvalumab Sensitive : C3
CCL5 elevation	Biliary Tract Cancer	CCL5 elevation	Biliary Tract Cancer	atezolizumab + cobimetinib Sensitive: C3 – Early Trials atezolizumab + cobimetinib Sensitive : C3	atezolizumab + cobimetinib Sensitive: C3 – Early Trials atezolizumab + cobimetinib Sensitive : C3
CCL5 overexpression	Glioblastoma	CCL5 overexpression	Glioblastoma	maraviroc Sensitive: D – Preclinical maraviroc Sensitive : D	maraviroc Sensitive: D – Preclinical maraviroc Sensitive : D