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DRUG CLASS:
Casein kinase I epsilon inhibitor
DRUG CLASS:
Casein kinase I epsilon inhibitor
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Related drugs:
‹
umbralisib (8)
umbralisib (8)
›
Associations
(8)
News
Trials
VERI cancer hierarchy
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No biomarker
Follicular Lymphoma
No biomarker
Follicular Lymphoma
umbralisib
Sensitive: A1 - Approval
umbralisib
Sensitive
:
A1
umbralisib
Sensitive: A1 - Approval
umbralisib
Sensitive
:
A1
No biomarker
Marginal Zone Lymphoma
No biomarker
Marginal Zone Lymphoma
umbralisib
Sensitive: A1 - Approval
umbralisib
Sensitive
:
A1
umbralisib
Sensitive: A1 - Approval
umbralisib
Sensitive
:
A1
No biomarker
Chronic Lymphocytic Leukemia
No biomarker
Chronic Lymphocytic Leukemia
umbralisib + ublituximab-xiiy
Sensitive: B - Late Trials
umbralisib + ublituximab-xiiy
Sensitive
:
B
umbralisib + ublituximab-xiiy
Sensitive: B - Late Trials
umbralisib + ublituximab-xiiy
Sensitive
:
B
IL2 elevation
Mantle Cell Lymphoma
IL2 elevation
Mantle Cell Lymphoma
umbralisib + ublituximab-xiiy + TG-1701
Sensitive: D – Preclinical
umbralisib + ublituximab-xiiy + TG-1701
Sensitive
:
D
umbralisib + ublituximab-xiiy + TG-1701
Sensitive: D – Preclinical
umbralisib + ublituximab-xiiy + TG-1701
Sensitive
:
D
IL6 elevation
Mantle Cell Lymphoma
IL6 elevation
Mantle Cell Lymphoma
umbralisib + ublituximab-xiiy + TG-1701
Sensitive: D – Preclinical
umbralisib + ublituximab-xiiy + TG-1701
Sensitive
:
D
umbralisib + ublituximab-xiiy + TG-1701
Sensitive: D – Preclinical
umbralisib + ublituximab-xiiy + TG-1701
Sensitive
:
D
TNFA elevation
Mantle Cell Lymphoma
TNFA elevation
Mantle Cell Lymphoma
umbralisib + ublituximab-xiiy + TG-1701
Sensitive: D – Preclinical
umbralisib + ublituximab-xiiy + TG-1701
Sensitive
:
D
umbralisib + ublituximab-xiiy + TG-1701
Sensitive: D – Preclinical
umbralisib + ublituximab-xiiy + TG-1701
Sensitive
:
D
Chr del(13q) + Chr del(11q) + SF3B1 mutation
Chronic Lymphocytic Leukemia
Chr del(13q) + Chr del(11q) + SF3B1 mutation
Chronic Lymphocytic Leukemia
umbralisib
Resistant: D – Preclinical
umbralisib
Resistant
:
D
umbralisib
Resistant: D – Preclinical
umbralisib
Resistant
:
D
ATM deletion + SF3B1 mutation
Chronic Lymphocytic Leukemia
ATM deletion + SF3B1 mutation
Chronic Lymphocytic Leukemia
umbralisib
Resistant: D – Preclinical
umbralisib
Resistant
:
D
umbralisib
Resistant: D – Preclinical
umbralisib
Resistant
:
D
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