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Association details:
Biomarker:
BST1 positive
Cancer:
Acute Myelogenous Leukemia
Drug:
S63845
(
MCL1 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
EACR 2021
Title:
CD157/BST-1 mediates pro-survival signals in acute myeloid leukemia
Published date:
05/28/2021
Excerpt:
...S63845 significantly increases the therapeutic efficacy of AraC in CD157-positive but not in CD157-negative AML..
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