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BIOMARKER:
BRCA2 mutation + CDK12 mutation
i
Other names:
CDK12, Cyclin Dependent Kinase 12, Cdc2-Related Kinase, Arginine/Serine-Rich, Cell Division Cycle 2-Related Protein Kinase 7, Cell Division Protein Kinase 12, CDC2-Related Protein Kinase 7, Cyclin-Dependent Kinase 12, CRKRS, CRK7, CDC2 Related Protein Kinase 7, HCDK12, CrkRS, CRKR, BRCA2, BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, Breast cancer 2, early onset
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Entrez ID:
675
;
51755
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HRD + BRCA2 mutation (7)
BRCA2 mutation + HR positive (3)
HR positive + BRCA2 mutation (3)
BRCA2 mutation + HER-2 negative (2)
HR negative + BRCA2 mutation (2)
ALK rearrangement + BRCA2 F2801fs (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA2 deletion + ATM mutation (1)
BRCA2 mutation + AKR1C3 overexpression (1)
BRCA2 mutation + ER positive (1)
BRCA2 mutation + ER positive + PGR positive (1)
BRCA2 mutation + RB1 deletion (1)
BRCA2 mutation + TMB-H (1)
BRCA2 mutation + TMB-L (1)
HR positive + BRCA2 mutation + PALB2 mutation (1)
ER positive + BRCA2 mutation (0)
HRD + BRCA2 mutation (7)
BRCA2 mutation + HR positive (3)
HR positive + BRCA2 mutation (3)
BRCA2 mutation + HER-2 negative (2)
HR negative + BRCA2 mutation (2)
ALK rearrangement + BRCA2 F2801fs (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA2 deletion + ATM mutation (1)
BRCA2 mutation + AKR1C3 overexpression (1)
BRCA2 mutation + ER positive (1)
BRCA2 mutation + ER positive + PGR positive (1)
BRCA2 mutation + RB1 deletion (1)
BRCA2 mutation + TMB-H (1)
BRCA2 mutation + TMB-L (1)
HR positive + BRCA2 mutation + PALB2 mutation (1)
ER positive + BRCA2 mutation (0)
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BRCA2 mutation + CDK12 mutation
Prostate Cancer
BRCA2 mutation + CDK12 mutation
Prostate Cancer
GnRH stimulant
Resistant: C3 – Early Trials
GnRH stimulant
Resistant
:
C3
GnRH stimulant
Resistant: C3 – Early Trials
GnRH stimulant
Resistant
:
C3
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