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GENE:
BRCA (Breast cancer early onset)
i
Other names:
BRCA, Breast cancer, early onset
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Entrez ID:
Related tests:
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FoundationOne® Liquid CDx (20)
PredicineCARE™
FoundationOne® Liquid CDx (20)
PredicineCARE™
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Associations
(15)
News
Trials
VERI cancer hierarchy
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HRD + BRCA wild-type
Ovarian Cancer
HRD + BRCA wild-type
Ovarian Cancer
bevacizumab
Sensitive: A2 - Guideline
bevacizumab
Sensitive
:
A2
bevacizumab
Sensitive: A2 - Guideline
bevacizumab
Sensitive
:
A2
HRD + BRCA wild-type
Ovarian Cancer
HRD + BRCA wild-type
Ovarian Cancer
bevacizumab + olaparib
Sensitive: A2 - Guideline
bevacizumab + olaparib
Sensitive
:
A2
bevacizumab + olaparib
Sensitive: A2 - Guideline
bevacizumab + olaparib
Sensitive
:
A2
HRD + BRCA wild-type
Ovarian Cancer
HRD + BRCA wild-type
Ovarian Cancer
niraparib
Sensitive: A2 - Guideline
niraparib
Sensitive
:
A2
niraparib
Sensitive: A2 - Guideline
niraparib
Sensitive
:
A2
BRCA mutation
HER2 Negative Breast Cancer
BRCA mutation
HER2 Negative Breast Cancer
rivoceranib + fluzoparib
Sensitive: B - Late Trials
rivoceranib + fluzoparib
Sensitive
:
B
rivoceranib + fluzoparib
Sensitive: B - Late Trials
rivoceranib + fluzoparib
Sensitive
:
B
BRCA wild-type + TP53 mutation
Ovarian Cancer
BRCA wild-type + TP53 mutation
Ovarian Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
HRD + BRCA wild-type
Triple Negative Breast Cancer
HRD + BRCA wild-type
Triple Negative Breast Cancer
D19466
Sensitive: C3 – Early Trials
D19466
Sensitive
:
C3
D19466
Sensitive: C3 – Early Trials
D19466
Sensitive
:
C3
HRD + BRCA wild-type
Triple Negative Breast Cancer
HRD + BRCA wild-type
Triple Negative Breast Cancer
carboplatin
Sensitive: C3 – Early Trials
carboplatin
Sensitive
:
C3
carboplatin
Sensitive: C3 – Early Trials
carboplatin
Sensitive
:
C3
HRD + BRCA wild-type
Triple Negative Breast Cancer
HRD + BRCA wild-type
Triple Negative Breast Cancer
cisplatin
Sensitive: C3 – Early Trials
cisplatin
Sensitive
:
C3
cisplatin
Sensitive: C3 – Early Trials
cisplatin
Sensitive
:
C3
HR positive + BRCA positive
HER2 Positive Breast Cancer
HR positive + BRCA positive
HER2 Positive Breast Cancer
olaparib
Sensitive: C4 – Case Studies
olaparib
Sensitive
:
C4
olaparib
Sensitive: C4 – Case Studies
olaparib
Sensitive
:
C4
BRCA mutation
Pancreatic Ductal Adenocarcinoma
BRCA mutation
Pancreatic Ductal Adenocarcinoma
PARP inhibitor
Sensitive: D – Preclinical
PARP inhibitor
Sensitive
:
D
PARP inhibitor
Sensitive: D – Preclinical
PARP inhibitor
Sensitive
:
D
BRCA mutation
Diffuse Large B Cell Lymphoma
BRCA mutation
Diffuse Large B Cell Lymphoma
loncastuximab tesirine-lpyl
Sensitive: D – Preclinical
loncastuximab tesirine-lpyl
Sensitive
:
D
loncastuximab tesirine-lpyl
Sensitive: D – Preclinical
loncastuximab tesirine-lpyl
Sensitive
:
D
BRCA deletion
Ovarian Cancer
BRCA deletion
Ovarian Cancer
olaparib + AZD7648
Sensitive: D – Preclinical
olaparib + AZD7648
Sensitive
:
D
olaparib + AZD7648
Sensitive: D – Preclinical
olaparib + AZD7648
Sensitive
:
D
BRCA wild-type + TP53 mutation
Lung Cancer
BRCA wild-type + TP53 mutation
Lung Cancer
talazoparib
Sensitive: D – Preclinical
talazoparib
Sensitive
:
D
talazoparib
Sensitive: D – Preclinical
talazoparib
Sensitive
:
D
BRCA wild-type + TP53 mutation
Breast Cancer
BRCA wild-type + TP53 mutation
Breast Cancer
talazoparib
Sensitive: D – Preclinical
talazoparib
Sensitive
:
D
talazoparib
Sensitive: D – Preclinical
talazoparib
Sensitive
:
D
TP53 R280K + BRCA wild-type
Triple Negative Breast Cancer
TP53 R280K + BRCA wild-type
Triple Negative Breast Cancer
APR-246
Sensitive: D – Preclinical
APR-246
Sensitive
:
D
APR-246
Sensitive: D – Preclinical
APR-246
Sensitive
:
D
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