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DRUG:
Braftovi (encorafenib)
i
Other names:
LGX818, NVP-LGX818, NVP-LGX818-NXA, ONO-7702, PF-07263896, W0090, LGX-818, LGX 818, NVPLGX818, NVP LGX818, ONO7702, ONO 7702, PF07263896, PF 07263896, W-0090, W 0090
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News alerts, weekly reports and conference planners
Associations
(63)
News
Trials
Company:
Medison, Nerviano Medical Sciences, Ono Pharma, Pfizer, Pierre Fabre
Drug class:
BRAF inhibitor, cRAF inhibitor
Related drugs:
‹
vemurafenib (212)
dabrafenib (211)
PLX4720 (65)
VS-6766 (27)
FORE-8394 (20)
RAF265 (7)
ERAS-254 (7)
GDC 0879 (6)
RXDX-105 (5)
RAF709 (3)
HI-511 (1)
SB-590885 (1)
BGB-3245 (1)
PF-07284890 (1)
ARQ 736 (0)
ASN003 (0)
BDTX-4933 (0)
BMS-908662 (0)
PF-07799933 (0)
RX208 (0)
NSC311152 (0)
donafenib (2)
vemurafenib (212)
dabrafenib (211)
PLX4720 (65)
VS-6766 (27)
FORE-8394 (20)
RAF265 (7)
ERAS-254 (7)
GDC 0879 (6)
RXDX-105 (5)
RAF709 (3)
HI-511 (1)
SB-590885 (1)
BGB-3245 (1)
PF-07284890 (1)
ARQ 736 (0)
ASN003 (0)
BDTX-4933 (0)
BMS-908662 (0)
PF-07799933 (0)
RX208 (0)
NSC311152 (0)
donafenib (2)
›
Associations
(63)
News
Trials
VERI cancer hierarchy
Reset Filters
BRAF V600E
Colorectal Cancer
BRAF V600E
Colorectal Cancer
cetuximab + binimetinib + encorafenib
Sensitive: A1 - Approval
cetuximab + binimetinib + encorafenib
Sensitive
:
A1
cetuximab + binimetinib + encorafenib
Sensitive: A1 - Approval
cetuximab + binimetinib + encorafenib
Sensitive
:
A1
BRAF V600E
Colorectal Cancer
BRAF V600E
Colorectal Cancer
cetuximab + encorafenib
Sensitive: A1 - Approval
cetuximab + encorafenib
Sensitive
:
A1
cetuximab + encorafenib
Sensitive: A1 - Approval
cetuximab + encorafenib
Sensitive
:
A1
BRAF V600
Melanoma
BRAF V600
Melanoma
binimetinib + encorafenib
Sensitive: A1 - Approval
binimetinib + encorafenib
Sensitive
:
A1
binimetinib + encorafenib
Sensitive: A1 - Approval
binimetinib + encorafenib
Sensitive
:
A1
BRAF V600K
Melanoma
BRAF V600K
Melanoma
binimetinib + encorafenib
Sensitive: A1 - Approval
binimetinib + encorafenib
Sensitive
:
A1
binimetinib + encorafenib
Sensitive: A1 - Approval
binimetinib + encorafenib
Sensitive
:
A1
BRAF V600E
Melanoma
BRAF V600E
Melanoma
binimetinib + encorafenib
Sensitive: A1 - Approval
binimetinib + encorafenib
Sensitive
:
A1
binimetinib + encorafenib
Sensitive: A1 - Approval
binimetinib + encorafenib
Sensitive
:
A1
BRAF V600E
Non Small Cell Lung Cancer
BRAF V600E
Non Small Cell Lung Cancer
binimetinib + encorafenib
Sensitive: A1 - Approval
binimetinib + encorafenib
Sensitive
:
A1
binimetinib + encorafenib
Sensitive: A1 - Approval
binimetinib + encorafenib
Sensitive
:
A1
BRAF V600
Cutaneous Melanoma
BRAF V600
Cutaneous Melanoma
binimetinib + encorafenib
Sensitive: A2 - Guideline
binimetinib + encorafenib
Sensitive
:
A2
binimetinib + encorafenib
Sensitive: A2 - Guideline
binimetinib + encorafenib
Sensitive
:
A2
BRAF V600E
Colorectal Cancer
BRAF V600E
Colorectal Cancer
panitumumab + encorafenib
Sensitive: A2 - Guideline
panitumumab + encorafenib
Sensitive
:
A2
panitumumab + encorafenib
Sensitive: A2 - Guideline
panitumumab + encorafenib
Sensitive
:
A2
BRAF V600E
Cutaneous Melanoma
BRAF V600E
Cutaneous Melanoma
binimetinib + encorafenib
Sensitive: A2 - Guideline
binimetinib + encorafenib
Sensitive
:
A2
binimetinib + encorafenib
Sensitive: A2 - Guideline
binimetinib + encorafenib
Sensitive
:
A2
BRAF V600K
Cutaneous Melanoma
BRAF V600K
Cutaneous Melanoma
binimetinib + encorafenib
Sensitive: A2 - Guideline
binimetinib + encorafenib
Sensitive
:
A2
binimetinib + encorafenib
Sensitive: A2 - Guideline
binimetinib + encorafenib
Sensitive
:
A2
BRAF V600
Rectal Cancer
BRAF V600
Rectal Cancer
cetuximab + encorafenib
Sensitive: A2 - Guideline
cetuximab + encorafenib
Sensitive
:
A2
cetuximab + encorafenib
Sensitive: A2 - Guideline
cetuximab + encorafenib
Sensitive
:
A2
BRAF V600
Rectal Cancer
BRAF V600
Rectal Cancer
panitumumab + encorafenib
Sensitive: A2 - Guideline
panitumumab + encorafenib
Sensitive
:
A2
panitumumab + encorafenib
Sensitive: A2 - Guideline
panitumumab + encorafenib
Sensitive
:
A2
BRAF V600E
Colon Cancer
BRAF V600E
Colon Cancer
panitumumab + encorafenib
Sensitive: A2 - Guideline
panitumumab + encorafenib
Sensitive
:
A2
panitumumab + encorafenib
Sensitive: A2 - Guideline
panitumumab + encorafenib
Sensitive
:
A2
BRAF V600E
Colon Cancer
BRAF V600E
Colon Cancer
cetuximab + encorafenib
Sensitive: A2 - Guideline
cetuximab + encorafenib
Sensitive
:
A2
cetuximab + encorafenib
Sensitive: A2 - Guideline
cetuximab + encorafenib
Sensitive
:
A2
BRAF V600K
Melanoma
BRAF V600K
Melanoma
encorafenib
Sensitive: B - Late Trials
encorafenib
Sensitive
:
B
encorafenib
Sensitive: B - Late Trials
encorafenib
Sensitive
:
B
BRAF V600E
Melanoma
BRAF V600E
Melanoma
encorafenib
Sensitive: B - Late Trials
encorafenib
Sensitive
:
B
encorafenib
Sensitive: B - Late Trials
encorafenib
Sensitive
:
B
BRAF V600E
Colorectal Cancer
BRAF V600E
Colorectal Cancer
encorafenib
Sensitive: B - Late Trials
encorafenib
Sensitive
:
B
encorafenib
Sensitive: B - Late Trials
encorafenib
Sensitive
:
B
BRAF V600E
Colorectal Cancer
BRAF V600E
Colorectal Cancer
binimetinib + encorafenib
Sensitive: B - Late Trials
binimetinib + encorafenib
Sensitive
:
B
binimetinib + encorafenib
Sensitive: B - Late Trials
binimetinib + encorafenib
Sensitive
:
B
BRAF V600E + BRAF V600K
Melanoma
BRAF V600E + BRAF V600K
Melanoma
binimetinib + encorafenib
Sensitive: B - Late Trials
binimetinib + encorafenib
Sensitive
:
B
binimetinib + encorafenib
Sensitive: B - Late Trials
binimetinib + encorafenib
Sensitive
:
B
BRAF V600
Multiple Myeloma
BRAF V600
Multiple Myeloma
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
BRAF V600E
Ovarian Serous Adenocarcinoma
BRAF V600E
Ovarian Serous Adenocarcinoma
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
BRAF V600E
Pancreatic Cancer
BRAF V600E
Pancreatic Cancer
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
BRAF V600E
Solid Tumor
BRAF V600E
Solid Tumor
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
BRAF V600K
Solid Tumor
BRAF V600K
Solid Tumor
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
BRAF V600
Non Small Cell Lung Cancer
BRAF V600
Non Small Cell Lung Cancer
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
BRAF V600E
Neuroendocrine Tumor
BRAF V600E
Neuroendocrine Tumor
cetuximab + encorafenib
Sensitive: C1 - Off-label
cetuximab + encorafenib
Sensitive
:
C1
cetuximab + encorafenib
Sensitive: C1 - Off-label
cetuximab + encorafenib
Sensitive
:
C1
BRAF V600E
Glioma
BRAF V600E
Glioma
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
BRAF V600E
Glioblastoma
BRAF V600E
Glioblastoma
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
binimetinib + encorafenib
Sensitive: C1 - Off-label
binimetinib + encorafenib
Sensitive
:
C1
BRAF V600
Melanoma
BRAF V600
Melanoma
encorafenib
Sensitive: C2 – Inclusion Criteria
encorafenib
Sensitive
:
C2
encorafenib
Sensitive: C2 – Inclusion Criteria
encorafenib
Sensitive
:
C2
BRAF mutation
Melanoma
BRAF mutation
Melanoma
binimetinib + encorafenib
Sensitive: C2 – Inclusion Criteria
binimetinib + encorafenib
Sensitive
:
C2
binimetinib + encorafenib
Sensitive: C2 – Inclusion Criteria
binimetinib + encorafenib
Sensitive
:
C2
BRAF V600
Melanoma
BRAF V600
Melanoma
nivolumab + ipilimumab + binimetinib + encorafenib
Sensitive: C2 – Inclusion Criteria
nivolumab + ipilimumab + binimetinib + encorafenib
Sensitive
:
C2
nivolumab + ipilimumab + binimetinib + encorafenib
Sensitive: C2 – Inclusion Criteria
nivolumab + ipilimumab + binimetinib + encorafenib
Sensitive
:
C2
BRAF V600
Colorectal Cancer
BRAF V600
Colorectal Cancer
cetuximab + encorafenib
Sensitive: C2 – Inclusion Criteria
cetuximab + encorafenib
Sensitive
:
C2
cetuximab + encorafenib
Sensitive: C2 – Inclusion Criteria
cetuximab + encorafenib
Sensitive
:
C2
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