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Association details:
Biomarker:BRAF wild-type
Cancer:Non Small Cell Lung Cancer
Drug Class:Immunotherapy
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

ERBB3 and BRAF Mutations as Potential Biomarkers in Non-Small Cell Lung Cancer Patients Under Immunotherapy-Based Treatments

Published date:
08/08/2023
Excerpt:
Liquid biopsy samples from 63 stage IV NSCLC patients were collected before first-line treatment with immunotherapy or chemo-immunotherapy….the median PFS and OS for patients with BRAF wt tumors were 5.36 and 12.00 months, respectively (LogRank p-value of 0.021 for PFS...
Secondary therapy:
Chemotherapy