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BIOMARKER:
BRAF wild-type + HER-2 positive
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1, ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
2064
;
673
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HER-2 amplification (129)
BRAF L485-P490 deletion (6)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
BRAF amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
HER-2 amplification (129)
BRAF L485-P490 deletion (6)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
BRAF amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
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VERI cancer hierarchy
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BRAF wild-type + HER-2 positive
Colorectal Cancer
BRAF wild-type + HER-2 positive
Colorectal Cancer
trastuzumab + pyrotinib
Sensitive: C3 – Early Trials
trastuzumab + pyrotinib
Sensitive
:
C3
trastuzumab + pyrotinib
Sensitive: C3 – Early Trials
trastuzumab + pyrotinib
Sensitive
:
C3
BRAF wild-type + HER-2 positive
Colorectal Cancer
BRAF wild-type + HER-2 positive
Colorectal Cancer
trastuzumab + pertuzumab
Sensitive: C3 – Early Trials
trastuzumab + pertuzumab
Sensitive
:
C3
trastuzumab + pertuzumab
Sensitive: C3 – Early Trials
trastuzumab + pertuzumab
Sensitive
:
C3
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