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BIOMARKER:
BRAF mutation + MEK1 P124L
i
Other names:
MAP2K1, MAPKK1, MEK1, PRKMK1, Mitogen-activated protein kinase kinase 1, BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
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Entrez ID:
673
;
5604
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BRAF L485-P490 deletion (6)
BRAF amplification (1)
MAP2K1 K59del (1)
BRAF L485-P490 deletion (6)
BRAF amplification (1)
MAP2K1 K59del (1)
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BRAF mutation + MEK1 P124L
Melanoma
BRAF mutation + MEK1 P124L
Melanoma
vemurafenib + cobimetinib
Sensitive: C4 – Case Studies
vemurafenib + cobimetinib
Sensitive
:
C4
vemurafenib + cobimetinib
Sensitive: C4 – Case Studies
vemurafenib + cobimetinib
Sensitive
:
C4
BRAF mutation + MEK1 P124L
Melanoma
BRAF mutation + MEK1 P124L
Melanoma
trametinib + dabrafenib
Resistant: C4 – Case Studies
trametinib + dabrafenib
Resistant
:
C4
trametinib + dabrafenib
Resistant: C4 – Case Studies
trametinib + dabrafenib
Resistant
:
C4
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