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Association details:
Biomarker:BCL6 translocation
Cancer:Diffuse Large B Cell Lymphoma
Regimen:R-CHOP (cyclophosphamide + doxorubicin hydrochloride + prednisone + Rituxan (rituximab) + vincristine)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
Title:

Clinical and Biological Features behind Hallmark Aberrations in Diffuse Large B-Cell Lymphoma

Published date:
11/01/2018
Excerpt:
...152 primary DLBCL patients treated with R-CHOP or R-CHOP-like regimen....BCL6 translocation status highlighted a subgroup of patients with a favorable outcome in the non-GCB DLBCLs independent of IPI (Figure 1F).
DOI:
10.1182/blood-2018-99-117958