^
Association details:
Biomarker:BCL6 rearrangement
Cancer:Diffuse Large B Cell Lymphoma
Regimen:MATRix (cytarabine + + Rituxan (rituximab) + thiotepa)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Title:

Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review

Published date:
07/21/2021
Excerpt:
Herein, we report a unique case of primary cauda equina diffuse large B-cell lymphoma....Fluorescence in situ hybridization (FISH) analysis from resected tissue was...positive for BCL6 rearrangement in 80% of nuclei.... Our patient was initially treated with R-CHOP with mid-cycle HD-MTX achieving a partial response. Under our care, she was further treated with two cycles of MATRIX resulting in complete remission.
DOI:
10.2147/JBM.S325264