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BIOMARKER:
BCL2 positive
i
Other names:
BCL2, Bcl-2, PPP1R50, B-cell CLL/lymphoma 2
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Entrez ID:
596
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BCL2 overexpression (17)
BCL2 expression (9)
BCL2 expression + MYC expression (8)
MYC overexpression + BCL2 overexpression (7)
BCL2 overexpression + MCL1 overexpression (2)
BCL2 underexpression (2)
MYC expression + BCL2 expression (2)
BCL2 overexpression + CCND1 overexpression (1)
BCL2 overexpression + MCL1 expression (1)
BCL2 overexpression + MCL1 underxpression + BCL2L1 underexpression (1)
BCL2 overexpression + MYC overexpression (1)
BCL2 positive + LGALS3 expression (1)
BTK expression + BCL2 expression (1)
BTK expression + BCL2 expression + MYC expression (1)
CASP3 overexpression + BCL2 negative (1)
CASP3 underexpression + BCL2 positive (1)
CD20 expression + PAX5 expression + BCL2 expression (1)
CD22 underexpression + BCL2 overexpression (1)
MYC expression + BCL2 expression + BCL6 expression (1)
MYC positive + BCL2 positive (1)
MYC positive + BCL2 positive + BCL6 positive (1)
BCL2 positive + IGH positive (0)
BCL2 overexpression (17)
BCL2 expression (9)
BCL2 expression + MYC expression (8)
MYC overexpression + BCL2 overexpression (7)
BCL2 overexpression + MCL1 overexpression (2)
BCL2 underexpression (2)
MYC expression + BCL2 expression (2)
BCL2 overexpression + CCND1 overexpression (1)
BCL2 overexpression + MCL1 expression (1)
BCL2 overexpression + MCL1 underxpression + BCL2L1 underexpression (1)
BCL2 overexpression + MYC overexpression (1)
BCL2 positive + LGALS3 expression (1)
BTK expression + BCL2 expression (1)
BTK expression + BCL2 expression + MYC expression (1)
CASP3 overexpression + BCL2 negative (1)
CASP3 underexpression + BCL2 positive (1)
CD20 expression + PAX5 expression + BCL2 expression (1)
CD22 underexpression + BCL2 overexpression (1)
MYC expression + BCL2 expression + BCL6 expression (1)
MYC positive + BCL2 positive (1)
MYC positive + BCL2 positive + BCL6 positive (1)
BCL2 positive + IGH positive (0)
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Trials
VERI cancer hierarchy
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BCL2 positive
Diffuse Large B Cell Lymphoma
BCL2 positive
Diffuse Large B Cell Lymphoma
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
BCL2 positive
Estrogen Receptor Positive Breast Cancer
BCL2 positive
Estrogen Receptor Positive Breast Cancer
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
BCL2 positive
Diffuse Large B Cell Lymphoma
BCL2 positive
Diffuse Large B Cell Lymphoma
methotrexate
Sensitive: C3 – Early Trials
methotrexate
Sensitive
:
C3
methotrexate
Sensitive: C3 – Early Trials
methotrexate
Sensitive
:
C3
BCL2 positive
Diffuse Large B Cell Lymphoma
BCL2 positive
Diffuse Large B Cell Lymphoma
pixantrone
Sensitive: C3 – Early Trials
pixantrone
Sensitive
:
C3
pixantrone
Sensitive: C3 – Early Trials
pixantrone
Sensitive
:
C3
BCL2 positive
Diffuse Large B Cell Lymphoma
BCL2 positive
Diffuse Large B Cell Lymphoma
venetoclax + polatuzumab vedotin-piiq
Sensitive: C3 – Early Trials
venetoclax + polatuzumab vedotin-piiq
Sensitive
:
C3
venetoclax + polatuzumab vedotin-piiq
Sensitive: C3 – Early Trials
venetoclax + polatuzumab vedotin-piiq
Sensitive
:
C3
BCL2 positive
Diffuse Large B Cell Lymphoma
BCL2 positive
Diffuse Large B Cell Lymphoma
venetoclax + ibrutinib
Sensitive: D – Preclinical
venetoclax + ibrutinib
Sensitive
:
D
venetoclax + ibrutinib
Sensitive: D – Preclinical
venetoclax + ibrutinib
Sensitive
:
D
BCL2 positive
Diffuse Large B Cell Lymphoma
BCL2 positive
Diffuse Large B Cell Lymphoma
venetoclax + fostamatinib
Sensitive: D – Preclinical
venetoclax + fostamatinib
Sensitive
:
D
venetoclax + fostamatinib
Sensitive: D – Preclinical
venetoclax + fostamatinib
Sensitive
:
D
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