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DRUG CLASS:

Bcl-xL degrader

DRUG CLASS:

Bcl-xL degrader

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KRAS G12C	Colorectal Cancer	KRAS G12C	Colorectal Cancer	sotorasib + DT2216 Sensitive: D – Preclinical sotorasib + DT2216 Sensitive : D	sotorasib + DT2216 Sensitive: D – Preclinical sotorasib + DT2216 Sensitive : D
KRAS G12C	Non Small Cell Lung Cancer	KRAS G12C	Non Small Cell Lung Cancer	sotorasib + DT2216 Sensitive: D – Preclinical sotorasib + DT2216 Sensitive : D	sotorasib + DT2216 Sensitive: D – Preclinical sotorasib + DT2216 Sensitive : D
KRAS G12C	Pancreatic Cancer	KRAS G12C	Pancreatic Cancer	sotorasib + DT2216 Sensitive: D – Preclinical sotorasib + DT2216 Sensitive : D	sotorasib + DT2216 Sensitive: D – Preclinical sotorasib + DT2216 Sensitive : D
JAK2 mutation	Acute Myelogenous Leukemia	JAK2 mutation	Acute Myelogenous Leukemia	DT2216 Sensitive: D – Preclinical DT2216 Sensitive : D	DT2216 Sensitive: D – Preclinical DT2216 Sensitive : D