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BIOMARKER:
BAP1 negative + BRCA1 mutation
i
Other names:
BRCA1, BRCC1, PPP1R53, RNF53, Breast cancer 1, early onset, BAP1, BRCA1 Associated Protein 1, BRCA1 Associated Protein-1 (Ubiquitin Carboxy-Terminal Hydrolase), Ubiquitin Carboxyl-Terminal Hydrolase BAP1, Cerebral Protein 6, Ubiquitin Carboxy-Terminal Hydrolase, BRCA1-Associated Protein 1, Cerebral Protein-13, HUCEP-13, KIAA0272, Hucep-6, UCHL2
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Entrez ID:
672
;
8314
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HRD + BRCA1 mutation (7)
BRCA1 mutation + HR positive (3)
BRCA1 mutation + TMB-H (3)
BRCA1 2080delA + CCNE1 overexpression (2)
BRCA1 mutation + HER-2 negative (2)
HR negative + BRCA1 mutation (2)
HR positive + BRCA1 mutation (2)
TMB-L + BAP1 V99M + NF2 R34 + Chr del(14q) + Chr del(19q) (2)
BRCA1 hypermethylation (1)
BRCA1 mutation + AKR1C3 overexpression (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
BRCA1 mutation + PD-L1 expression (1)
BRCA1 mutation + RAD51B deletion (1)
BRCA1 mutation + RB1 deletion (1)
BRCA1 promoter methylation (1)
EGFR mutation + BRCA1 overexpression (1)
EGFR mutation + BRCA1 underexpression (1)
HR positive + BRCA1 mutation + PALB2 mutation (1)
PTEN deletion + BRCA1 mutation (1)
BAP1 581-17_585del22 + RAD21 amplification (1)
BAP1 R300Gfs*6 + PD-L1 expression (1)
BAP1 deletion + TMB-L + PD-L1 expression (1)
BAP1 mutation + FGFR2 fusion (1)
BAP1 mutation + IDH2 R172W + CDKN2A deletion + CDKN2B deletion (1)
ER positive + BRCA1 mutation (0)
CAMK2D overexpression + BAP1 deletion (0)
HRD + BRCA1 mutation (7)
BRCA1 mutation + HR positive (3)
BRCA1 mutation + TMB-H (3)
BRCA1 2080delA + CCNE1 overexpression (2)
BRCA1 mutation + HER-2 negative (2)
HR negative + BRCA1 mutation (2)
HR positive + BRCA1 mutation (2)
TMB-L + BAP1 V99M + NF2 R34 + Chr del(14q) + Chr del(19q) (2)
BRCA1 hypermethylation (1)
BRCA1 mutation + AKR1C3 overexpression (1)
BRCA1 mutation + BRCA2 mutation + TMB-H (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
BRCA1 mutation + PD-L1 expression (1)
BRCA1 mutation + RAD51B deletion (1)
BRCA1 mutation + RB1 deletion (1)
BRCA1 promoter methylation (1)
EGFR mutation + BRCA1 overexpression (1)
EGFR mutation + BRCA1 underexpression (1)
HR positive + BRCA1 mutation + PALB2 mutation (1)
PTEN deletion + BRCA1 mutation (1)
BAP1 581-17_585del22 + RAD21 amplification (1)
BAP1 R300Gfs*6 + PD-L1 expression (1)
BAP1 deletion + TMB-L + PD-L1 expression (1)
BAP1 mutation + FGFR2 fusion (1)
BAP1 mutation + IDH2 R172W + CDKN2A deletion + CDKN2B deletion (1)
ER positive + BRCA1 mutation (0)
CAMK2D overexpression + BAP1 deletion (0)
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BAP1 negative + BRCA1 mutation
Mesothelioma
BAP1 negative + BRCA1 mutation
Mesothelioma
rucaparib
Sensitive: C3 – Early Trials
rucaparib
Sensitive
:
C3
rucaparib
Sensitive: C3 – Early Trials
rucaparib
Sensitive
:
C3
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