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Association details:
Biomarker:
BAP1 mutation
Cancer:
Renal Cell Carcinoma
Drug Class:
Glutamate inhibitor
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Source:
KCRS 2020
Title:
Studying BAP1 in Regulating Glucose Dependency in Renal Cancer: Mechanisms and Preclinical Translation
Excerpt:
...Our studies may identify GLUT inhibitors as effective therapies to treat renal cancer patients with BAP1 mutation or deficiency.
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