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Association details:
| Biomarker: | ARID1A mutation |
|---|---|
| Cancer: | Gastric Cancer |
| Drug Class: | EZH2 inhibitor |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-defcient gastric cancer
Published date:
06/06/2020
Excerpt:
EZH2 inhibitors decreased the viability of ARID1A-deficient cells in a dose-dependent manner and demonstrated the selective sensitivity to ARID1A-defcient cells in vitro experiment system.
DOI:
10.1007/s10120-020-01094-0
