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Association details:
| Biomarker: | AR splice variant 7 negative |
|---|---|
| Cancer: | Prostate Cancer |
| Drug: | Xtandi (enzalutamide) (Androgen receptor inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
1836P - Blood based biomarkers identify metastatic castration-resistant prostate cancer (mCRPC) with the greatest benefit from continuing enzalutamide (ENZ) beyond progression in combination with docetaxel (Doc): A pre-specified biomarker study of the phase IIIb PRESIDE trial
Published date:
10/16/2023
Excerpt:
Pt who were AR wt and AR-V7- (N=87, 55%) had significantly prolonged PFS from continuing ENZ (11.2 months (m) v 8.7 m P, HR: 0.49; 95% CI: 0.29-0.82, p=0.006)…
Trial ID:
