Enzalutamide and Mifepristone in Treating Patients With Metastatic Hormone Resistant Prostate Cancer
...Radiographic PFS`Number of Participants With Positive AR Expression Within Circulating Tumor Cells (CTCs)`Number of Participants With Positive GR Expression Within Circulating Tumor Cells (CTCs)`Testosterone`Thyroid Stimulating Hormone`Cortisol...
Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance
Levels of AR mRNA and protein expression were also similar between nonresponders and responders (Fig. 4B and SI Appendix, Table S2), suggesting that AR genomic changes or AR expression changes are not good predictors of enzalutamide response.