Patient 46 did not tolerate gemcitabine and nab-paclitaxel and came off treatment after 1 cycle….He initiated treatment with afatinib at a dose of 30 mg daily. After 4 weeks, a repeat PET/CT was performed also showing significant response to therapy (Fig. 3B, right)....Response was confirmed by CT imaging performed after 8 weeks following treatment initiation, and a CT scan done 5 months after treatment initiation showed ongoing response.