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BIOMARKER:

ALK F1245C

i
Other names: Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
Entrez ID:
ALK F1245C
NSCLC
ceritinib
Sensitive: C3 – Early Trials
ALK F1245C
NSCLC
crizotinib
Resistant: C3 – Early Trials
ALK F1245C
Neuroblastoma
lorlatinib
Sensitive: D – Preclinical