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BIOMARKER:
AKT1 E17K
i
Other names:
AKT1, AKT, PKB, PRKBA, RAC, V-akt murine thymoma viral oncogene homolog 1
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Entrez ID:
207
Related biomarkers:
Expression
Mutation
CNA
Others
‹
AKT1 E17K + HR positive (2)
AKT1 mutation + ER positive (2)
AKT1 mutation + HR positive (2)
AKT1 mutation + ER negative (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
AKT1 E17K + CTNNB1 G34R + ER Y537S + MSI-H (0)
AKT1 E17K + HR positive (2)
AKT1 mutation + ER positive (2)
AKT1 mutation + HR positive (2)
AKT1 mutation + ER negative (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
AKT1 E17K + CTNNB1 G34R + ER Y537S + MSI-H (0)
›
Associations
News
Trials
VERI cancer hierarchy
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AKT1 E17K
Triple Negative Breast Cancer
AKT1 E17K
Triple Negative Breast Cancer
AN2025
Sensitive: C3 – Early Trials
AN2025
Sensitive
:
C3
AN2025
Sensitive: C3 – Early Trials
AN2025
Sensitive
:
C3
AKT1 E17K
Salivary Gland Cancer
AKT1 E17K
Salivary Gland Cancer
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 E17K
Uterine Corpus Leiomyosarcoma
AKT1 E17K
Uterine Corpus Leiomyosarcoma
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 E17K
Melanoma
AKT1 E17K
Melanoma
vemurafenib
Resistant: C3 – Early Trials
vemurafenib
Resistant
:
C3
vemurafenib
Resistant: C3 – Early Trials
vemurafenib
Resistant
:
C3
AKT1 E17K
Breast Cancer
AKT1 E17K
Breast Cancer
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 E17K
Colorectal Cancer
AKT1 E17K
Colorectal Cancer
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
AKT1 E17K
Estrogen Receptor Positive Breast Cancer
AKT1 E17K
Estrogen Receptor Positive Breast Cancer
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 E17K
Solid Tumor
AKT1 E17K
Solid Tumor
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
capivasertib
Sensitive: C3 – Early Trials
capivasertib
Sensitive
:
C3
AKT1 E17K
Breast Cancer
AKT1 E17K
Breast Cancer
TAS-117
Sensitive: C3 – Early Trials
TAS-117
Sensitive
:
C3
TAS-117
Sensitive: C3 – Early Trials
TAS-117
Sensitive
:
C3
AKT1 E17K
Breast Cancer
AKT1 E17K
Breast Cancer
atezolizumab + RG7440
Sensitive: C3 – Early Trials
atezolizumab + RG7440
Sensitive
:
C3
atezolizumab + RG7440
Sensitive: C3 – Early Trials
atezolizumab + RG7440
Sensitive
:
C3
AKT1 E17K
Breast Cancer
AKT1 E17K
Breast Cancer
palbociclib + ARQ 751
Sensitive: D – Preclinical
palbociclib + ARQ 751
Sensitive
:
D
palbociclib + ARQ 751
Sensitive: D – Preclinical
palbociclib + ARQ 751
Sensitive
:
D
AKT1 E17K
Colorectal Cancer
AKT1 E17K
Colorectal Cancer
trametinib + palbociclib
Sensitive: D – Preclinical
trametinib + palbociclib
Sensitive
:
D
trametinib + palbociclib
Sensitive: D – Preclinical
trametinib + palbociclib
Sensitive
:
D
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