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BIOMARKER:
ABL1 exon 4 deletion + ABL1 T315I
i
Other names:
ABL proto-oncogene 1, ABL, c-ABL, JTK7, p150, ABL1
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Entrez ID:
25
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ABL1 T315I (5)
ABL1 E255K (2)
ABL1 G250E + ABL1 D276G + ABL1 T315I (2)
ABL1 D276G (1)
ABL1 F317L (1)
ABL1 F359V (1)
ABL1 G250E (1)
ABL1 L387M (1)
ABL1 M351T (1)
ABL1 T315I + ABL1 M351T + ABL1 L387M (1)
ABL1 Y253H (1)
BCR-ABL1 A337T (1)
BCR-ABL1 P465S (1)
BCR-ABL1 Q252H + BCR-ABL1 V299L (1)
BCR-ABL1 T315L (1)
BCR-ABL1 Y253H + BCR-ABL1 T315I (1)
ABL1 T315I (5)
ABL1 E255K (2)
ABL1 G250E + ABL1 D276G + ABL1 T315I (2)
ABL1 D276G (1)
ABL1 F317L (1)
ABL1 F359V (1)
ABL1 G250E (1)
ABL1 L387M (1)
ABL1 M351T (1)
ABL1 T315I + ABL1 M351T + ABL1 L387M (1)
ABL1 Y253H (1)
BCR-ABL1 A337T (1)
BCR-ABL1 P465S (1)
BCR-ABL1 Q252H + BCR-ABL1 V299L (1)
BCR-ABL1 T315L (1)
BCR-ABL1 Y253H + BCR-ABL1 T315I (1)
›
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VERI cancer hierarchy
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ABL1 exon 4 deletion + ABL1 T315I
Acute Lymphocytic Leukemia
ABL1 exon 4 deletion + ABL1 T315I
Acute Lymphocytic Leukemia
ponatinib
Resistant: C4 – Case Studies
ponatinib
Resistant
:
C4
ponatinib
Resistant: C4 – Case Studies
ponatinib
Resistant
:
C4
ABL1 exon 4 deletion + ABL1 T315I
Acute Lymphocytic Leukemia
ABL1 exon 4 deletion + ABL1 T315I
Acute Lymphocytic Leukemia
ponatinib + blinatumomab
Sensitive: C4 – Case Studies
ponatinib + blinatumomab
Sensitive
:
C4
ponatinib + blinatumomab
Sensitive: C4 – Case Studies
ponatinib + blinatumomab
Sensitive
:
C4
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