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BIOMARKER:

TP53 mutation

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Other names: TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1
Entrez ID:
9ms
Clinical
|
TP53 (Tumor protein P53)
|
TP53 mutation • TP53 mutation + Chr del(17p)
10ms
EGFR (Epidermal growth factor receptor) • TP53 (Tumor protein P53)
|
TP53 mutation • EGFR mutation
10ms
TP53 (Tumor protein P53) • FLT3 (Fms-related tyrosine kinase 3)
|
TP53 mutation
|
Venclexta (venetoclax) • azacitidine
10ms
TP53 (Tumor protein P53) • SHH (Sonic Hedgehog Signaling Molecule)
|
TP53 mutation • TP53 wild-type • SHH mutation
11ms
TP53 (Tumor protein P53) • FLT3 (Fms-related tyrosine kinase 3) • IDH1 (Isocitrate dehydrogenase (NADP(+)) 1) • IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2) • NPM1 (Nucleophosmin 1)
|
TP53 mutation • NPM1 mutation
11ms
TP53 (Tumor protein P53) • ATM (ATM serine/threonine kinase)
|
TP53 mutation
|
Venclexta (venetoclax) • Jaypirca (pirtobrutinib)
11ms
Clinical
|
EGFR (Epidermal growth factor receptor) • HER-2 (Human epidermal growth factor receptor 2) • TP53 (Tumor protein P53)
|
TP53 mutation • EGFR mutation • HER-2 mutation
11ms
KRAS (KRAS proto-oncogene GTPase) • TP53 (Tumor protein P53) • ATM (ATM serine/threonine kinase)
|
TP53 mutation • KRAS mutation • ATM mutation • ATM expression • KRAS expression
11ms
Clinical • IO biomarker
|
PD-L1 (Programmed death ligand 1) • TP53 (Tumor protein P53) • ATM (ATM serine/threonine kinase)
|
PD-L1 expression • TP53 mutation • PD-L1 overexpression
11ms
IO biomarker
|
EGFR (Epidermal growth factor receptor) • PD-L1 (Programmed death ligand 1) • KRAS (KRAS proto-oncogene GTPase) • TP53 (Tumor protein P53) • TMB (Tumor Mutational Burden) • ATM (ATM serine/threonine kinase) • STK11 (Serine/threonine kinase 11) • ARID2 (AT-Rich Interaction Domain 2)
|
PD-L1 expression • TP53 mutation • KRAS mutation • EGFR mutation • TMB-H • ATM mutation • STK11 mutation • KRAS mutation + STK11 mutation + TP53 mutation • KRAS expression
11ms
EGFR (Epidermal growth factor receptor) • ALK (Anaplastic lymphoma kinase) • TP53 (Tumor protein P53) • RB1 (RB Transcriptional Corepressor 1)
|
TP53 mutation
12ms
Clinical • Real-world evidence • Real-world
|
KRAS (KRAS proto-oncogene GTPase) • TP53 (Tumor protein P53) • STK11 (Serine/threonine kinase 11) • CDKN2A (Cyclin Dependent Kinase Inhibitor 2A) • KEAP1 (Kelch Like ECH Associated Protein 1) • SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily A, member 4)
|
TP53 mutation • KRAS G12C • STK11 mutation • KEAP1 mutation • CDKN2A mutation • KRAS G12 • SMARCA4 mutation
12ms
EGFR (Epidermal growth factor receptor) • TP53 (Tumor protein P53) • VEGFA (Vascular endothelial growth factor A)
|
TP53 mutation • EGFR mutation
|
Tagrisso (osimertinib)