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BIOMARKER:
TP53 deletion
i
Other names:
TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1
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Entrez ID:
7157
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
›
Associations
(21)
News
Trials
Search handles
@DrRaulCordoba
@RahulBanerjeeMD
Search handles
@DrRaulCordoba
@RahulBanerjeeMD
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Latest
11ms
@LeppaSM: TP53 deletions remained as the only high risk factor with impact in PFS and OS #lymsm. My question: how should we manage those patients? 🤔 #17ICML (@DrRaulCordoba)
11 months ago
Clinical
|
TP53 (Tumor protein P53)
|
TP53 deletion
over1year
Congrats @mmejia91 @RubenNiesvizky @WeillCornell on an awesome use of CoMpass @theMMRF data! Hadn’t seen this abstract. #ASH22 analysis of EMD in #MMsm showing higher rates of p53 deletion or inactivation. Unsurprisingly, higher Hgb and lower M-spike at Dx. (@RahulBanerjeeMD)
over 1 year ago
TP53 (Tumor protein P53)
|
TP53 deletion
2years
Our latest paper published in Oncogene. We found that myeloma cells with both p53 deletion and 1q21 amplification are susceptible to CHEK2 inhibition due to deregulated DNA damage response. This may offer a new approach for these high-risk patients. https://t.co/ez7t6SsslE #mmsm (@chngwj)
2 years ago
Clinical
|
CHEK2 (Checkpoint kinase 2)
|
TP53 deletion
over2years
#losemi hastalarında kemoimmunoterapi ile umut vaat eden gelişmeler %100’e varan yanıt ve 45 ayı aşan sağkalım #KLL #fevzialtuntas Durable remissions following combined targeted therapy in patients with CLL harboring TP53 deletions and/or mutations https://t.co/ZK02CViyl5. (@altuntasfevzi)
over 2 years ago
Clinical • NDA
|
TP53 (Tumor protein P53)
|
TP53 mutation • TP53 deletion
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