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    BIOMARKER:

    TMB-H + PD-L1 overexpression

    i
    Other names: PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule, TMB | Tumor Mutational Burden
    Entrez ID:
    29126
    Related biomarkers:
    Expression
    Mutation
    CNA
    Others
    almost3years
    MORE w/ #ASCO21 abstract released today: Landscape of KRASG12C, associated genomic alterations, and interrelation with immuno-oncology (IO) biomarkers. Relationship to high TMB and PD-L1 overexpression. #Colorectal #CRCSM @agrothey @JeanneTie https://t.co/9D9lPl59AJ (@fireflyann)
    IO biomarker
    |
    PD-L1 (Programmed death ligand 1) • KRAS (KRAS proto-oncogene GTPase) • TMB (Tumor Mutational Burden)
    |
    TMB-H • PD-L1 overexpression • KRAS G12C • KRAS G12 • TMB-H + PD-L1 overexpression