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BIOMARKER:
TERT amplification
i
Other names:
TERT, Telomerase Reverse Transcriptase, Telomerase-Associated Protein 2, Telomerase Catalytic Subunit, HEST2, EST2, TCS1, TP2, TRT, PFBMFT1, DKCA2, DKCB4, CMM9, HTR
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News alerts, weekly reports and conference planners
Entrez ID:
7015
Related biomarkers:
Expression
Mutation
Others
‹
BRAF mutation + TERT overexpression (2)
CCDC6‐RET fusion + TERT promotor mutation (1)
CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation (1)
TERT C228T + FGFR3 amplification + FGFR3-TACC3 fusion (1)
TERT mutation + AFP elevation (1)
TERT mutation + EGFR T790M + EGFR exon 20 insertion (1)
TERT mutation + MGMT promoter methylation (1)
TERT positive + PD-L1 expression (1)
TMB-H + TERT promoter mutation (1)
BRAF mutation + TERT overexpression (2)
CCDC6‐RET fusion + TERT promotor mutation (1)
CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation (1)
TERT C228T + FGFR3 amplification + FGFR3-TACC3 fusion (1)
TERT mutation + AFP elevation (1)
TERT mutation + EGFR T790M + EGFR exon 20 insertion (1)
TERT mutation + MGMT promoter methylation (1)
TERT positive + PD-L1 expression (1)
TMB-H + TERT promoter mutation (1)
›
Associations
(2)
News
Trials
Search handles
@StephenVLiu
Search handles
@StephenVLiu
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Latest
2years
Our last paper on the role of acquired TERT amplification in addition to p53 and Rb alterations in EGFR-mut lung adenocarcinomas transformed into SCLC https://t.co/BlIa8fb9kv (@DMSLung)
2 years ago
EGFR (Epidermal growth factor receptor)
|
TERT amplification
over2years
We continue to learn more about #EGFR mutant NSCLC transforming to #SCLC. In this report @LungCaJournal, in addition to known TP53 and Rb loss, acquired TERT amplification observed, which may play a role in the clonal evolution. Can we target? Prevent? https://t.co/fdvuku42vQ (@StephenVLiu)
over 2 years ago
EGFR (Epidermal growth factor receptor) • TP53 (Tumor protein P53)
|
TP53 mutation • EGFR mutation • TERT amplification
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