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BIOMARKER:
STRN-ALK fusion
i
Other names:
STRN, Striatin, Protein Phosphatase 2 Regulatory Subunit B'''Alpha, Striatin Calmodulin Binding Protein, Striatin Calmodulin-Binding Protein, PPP2R6A, SG2NA, STRN1, NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
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News alerts, weekly reports and conference planners
Entrez ID:
238
;
6801
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
›
Associations
(5)
News
Trials
Search handles
@DrSteveMartin
Search handles
@DrSteveMartin
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Latest
over1year
Hey #lcsm precision onc guru friends- you want to be an Alkemist and help w challenging case? Young pt w egfr ex19 del, nice response to osi for yr+, now progression incl CNS CNS specimen now shows STRN-ALK fusion along w ex19del. Getting SRS to resid CNS dx What is best syst tx? (@DrSteveMartin)
over 1 year ago
EGFR (Epidermal growth factor receptor) • STRN (Striatin)
|
EGFR exon 19 deletion • ALK fusion • STRN-ALK fusion
almost4years
Metastatic colon cancer with STRN-ALK gene fusion. - ALK fusion in <1% of CRC - Fusion of ALK to diverse 5′ partners - Constitutive activation of MAPK, STAT3, PI3K pathways - Mutually exclusive of RAS, RAF, PIK3CA muts - Eligible for ALK inhibitor therapy #MolPathMonday #GIpath (@LJTafeMD)
almost 4 years ago
ALK (Anaplastic lymphoma kinase) • PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) • STRN (Striatin)
|
ALK fusion • STRN-ALK fusion
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