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BIOMARKER:
PTPN11 mutation
i
Other names:
PTPN11, Protein Tyrosine Phosphatase Non-Receptor Type 11, Tyrosine-Protein Phosphatase Non-Receptor Type 11, Protein-Tyrosine Phosphatase 1D, Protein-Tyrosine Phosphatase 2C, SH-PTP2, SH-PTP3, PTP-1D, PTP2C, Protein Tyrosine Phosphatase Non-Receptor Type 11, Noonan Syndrome 1, METCDS, PTP-2C, SHPTP2, BPTP3, SHP-2, JMML, SHP2, Shp2, CFC, NS1
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Entrez ID:
5781
Related biomarkers:
Expression
Mutation
Others
‹
›
Associations
(11)
News
Trials
Search handles
@doctorpemm
@hemedoc
@mtmdphd
Search handles
@doctorpemm
@hemedoc
@mtmdphd
Filter by
Latest
over1year
Molecular, clinical, and prognostic implications of PTPN11 mutations in acute myeloid leukemia [Feb 25, 2022] Fobare et al. Byrd @BloodAdvances https://t.co/TaOVrhQxpE #AMLsm #leusm #PrecisionMedicine @ALLIANCE_org In n=140 Pts w/ PTPN11 - px in NPM1 wt (@mtmdphd)
over 1 year ago
Clinical
|
NPM1 (Nucleophosmin 1) • PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11)
|
PTPN11 mutation
2years
Yah, the somatic ones (PTPN11, N/KRAS) are more common. You have to make sure you distinguish between them (like u can’t diagnose JMML in person w/ germline PTPN11 mutation only so it’s important to get a germline sample to compare.) (@PedsHemeDoc)
2 years ago
KRAS (KRAS proto-oncogene GTPase) • PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11)
|
PTPN11 mutation
over2years
The Clinical impact of #PTPN11 mutations in adults w/acute myeloid leukemia | Leukemia @Malfayez7 @GhayasIssa @TapKadia @garciamanero @DrHKantarjian @GCC_Cortes @doctorpemm @GBorthakur #leusm https://t.co/XjSGdRflfA (@doctorpemm)
over 2 years ago
Clinical
|
PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11)
|
PTPN11 mutation
over2years
Impact of #PTPN11 mutations on clinical outcome analyzed in 1529 patients with acute myeloid leukemia | Blood Advances | American Society of Hematology https://t.co/Tq65VxnIG3 @BloodAdvances @ASH_hematology #leusm (@doctorpemm)
over 2 years ago
Clinical • Clinical data
|
PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11)
|
PTPN11 mutation
over3years
#ASH20 #leusm Ries: Mono7 AML enriched for PTPN11 mutations. MECOM most overexpressed gene. MECOM associated with stemness genomic methylation. (@hemedoc)
over 3 years ago
PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11)
|
PTPN11 mutation
over3years
@Dr_R_Kurzrock PTPN11 mutation in prostatic cancer is associated with resistance to anti androgenic therapy. Is there any target therapy to be offered? Is BRAF inhibitors an alternative? Best regards Cristovam (@Cscapulatempo)
over 3 years ago
BRAF (B-raf proto-oncogene) • PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11)
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PTPN11 mutation
|
Rituxan (rituximab)
over3years
The Clinical impact of #PTPN11 mutations in adults with acute myeloid leukemia | Leukemia @Malfayez7 @GBorthakur @LeukemiaMDA #leusm #endcancer https://t.co/XjSGdRflfA (@doctorpemm)
over 3 years ago
Clinical
|
PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11)
|
PTPN11 mutation
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