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BIOMARKER:
PLCG2 mutation
i
Other names:
PLCG2, Phospholipase C Gamma 2, 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-2, Phospholipase C, Gamma 2 (Phosphatidylinositol-Specific), Phosphoinositide Phospholipase C-Gamma-2, Phospholipase C-IV, PLC-Gamma-2, PLC-IV, Phospholipase C-Gamma-2, APLAID, FCAS3
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Entrez ID:
5336
Related biomarkers:
Mutation
‹
›
Associations
(4)
News
Trials
Search handles
@tobyeyre82
Search handles
@tobyeyre82
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Latest
1year
BTK and PLCG2 remain unmutated in one third of patients with CLL relapsing on ibrutinib https://t.co/zIMIU2Waoa (@tobyeyre82)
1 year ago
Clinical
|
PLCG2 (Phospholipase C Gamma 2)
|
PLCG2 mutation
|
Imbruvica (ibrutinib)
over1year
V interesting early data of downstream inhibitor of PKC-Beta MS-553 in #CLL ORR 48% in R/R #CLL including in pts with BTK and PLCG2 mutations #ASH22 (@tobyeyre82)
over 1 year ago
Clinical
|
PLCG2 (Phospholipase C Gamma 2) • PRKCB (Protein Kinase C Beta)
|
PLCG2 mutation
|
MS-553
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