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BIOMARKER:
PIK3CA E545
i
Other names:
PIK3CA, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha, Phosphoinositide-3-kinase, catalytic, alpha polypeptide, Serine/threonine protein kinase PIK3CA, PtdIns-3-kinase subunit P110-alpha, PI3K-alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 KDa catalytic subunit alpha, Phosphatidylinositol 3-kinase, Catalytic, 110-KD, alpha, PI3-kinase P110 subunit alpha, PI3-kinase subunit alpha, PtdIns-3-kinase subunit alpha, PI3Kalpha, P110alpha, PI3K
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Entrez ID:
5290
Related biomarkers:
Expression
Mutation
CNA
Others
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Associations
(4)
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@oncologician
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@oncologician
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3years
Yes Not all PIK3CA mutn r the same E545K n H1074R being MC .Hwvr the VAF of PIK3ca here s/o its imp role in oncogenesis. "Vast majority" of breast oncologists r adept @ combining PIK3CAi . Wat worries me is p53 which makes the genome unstable n ^ chances of Acqd res. quickly (@oncologician)
3 years ago
PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha)
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PIK3CA E545K • PIK3CA E545
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