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BIOMARKER:
PDGFRA exon 18 mutation
i
Other names:
Platelet Derived Growth Factor Receptor Alpha, Platelet-Derived Growth Factor Receptor Alpha Polypeptide, Alpha-Type Platelet-Derived Growth Factor Receptor, CD140 Antigen-Like Family Member A, CD140a Antigen, PDGF-R-Alpha, PDGFR-2, PDGFR2, Alpha Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor Alpha Receptor, PDGFR-Alpha, RHEPDGFRA, CD140A
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Entrez ID:
5156
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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Associations
(3)
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@schoffski
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@schoffski
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almost4years
According to a press release from Blueprint Med. the 476 patient Phase 3 VOYAGER trial of avapritinib vs. regorafenib in GIST did not meet the progression-free survival endpoint; the company is discontinuing development of avapritinib in GIST beyond PDGFRA exon 18 mutant GIST (@schoffski)
almost 4 years ago
Clinical • P3 data
|
PDGFRA (Platelet Derived Growth Factor Receptor Alpha)
|
PDGFRA mutation • PDGFRA exon 18 mutation
|
Stivarga (regorafenib) • Ayvakit (avapritinib)
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