^
    almost3years
    NrasQ61R/+ and Kras−/− cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors https://t.co/JrTzmgwH5k (@BloodJournal)
    KRAS (KRAS proto-oncogene GTPase) • RASGRP1 (RAS Guanyl Releasing Protein 1)
    |
    NRAS Q61 • NRAS Q61R
    3years
    This work has directly influenced my #melanoma practice. I (and now you!) can infer a lot from knowing someone's tumor is NF1 or NRAS G12 mutant vs NRAS Q61; from a scalp primary vs trunk vs unknown primary; or M1b stage. 26/x (@alexshoushtari)
    NF1 (Neurofibromin 1)
    |
    NRAS mutation • NRAS Q61 • NRAS G12
    over3years
    NGS report: NRAS Q61R mutation, TMB <1. #melanomadoctor (@DrBetofMDPhD)
    NRAS (Neuroblastoma RAS viral oncogene homolog)
    |
    NRAS mutation • NRAS Q61 • NRAS Q61R