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BIOMARKER:
NPM1-ALK fusion
i
Other names:
Nucleophosmin (Nucleolar Phosphoprotein B23, Numatrin), Testicular Tissue Protein Li 128, Nucleolar Protein NO38, Numatrin, NPM1, Nucleophosmin 1, Nucleophosmin/Nucleoplasmin Family, Member 1, Nucleolar Phosphoprotein B23, NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
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News alerts, weekly reports and conference planners
Entrez ID:
238
;
4869
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ALK positive (73)
ALK negative (4)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
NPM1 expression (2)
ALK expression + PDGFRA expression (1)
ALK expression + PDGFRB expression (1)
ALK overexpression (1)
ALK positive + ROS1 positive (1)
ALK positive + YAP1 overexpression (1)
ALK positive + YES1 overexpression (1)
KRT7 positive + NKX2-1 positive + ALK overexpression (1)
CCDC86 expression + NPM1 expression (1)
ALK positive (73)
ALK negative (4)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
NPM1 expression (2)
ALK expression + PDGFRA expression (1)
ALK expression + PDGFRB expression (1)
ALK overexpression (1)
ALK positive + ROS1 positive (1)
ALK positive + YAP1 overexpression (1)
ALK positive + YES1 overexpression (1)
KRT7 positive + NKX2-1 positive + ALK overexpression (1)
CCDC86 expression + NPM1 expression (1)
›
Associations
(4)
News
Trials
Search handles
@VivekSubbiah
Search handles
@VivekSubbiah
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Latest
almost3years
8/8 Tumors beyond ALK+ lymphomas such as histiocytic disorders, multiple myeloma, B-cell neoplasms, harbor ALK fusions. Ceritinib therapy documented durable complete response in an NPM1-ALK+ ALCL patient @OncoAlert @myESMO @ESMO_Open @montypal https://t.co/gaiUCSiT84 (@VivekSubbiah)
almost 3 years ago
Clinical
|
NPM1 (Nucleophosmin 1)
|
ALK fusion • NPM1-ALK fusion
|
Zykadia (ceritinib)
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