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    BIOMARKER:

    MYD88 mutation + CXCR4 mutation

    i
    Other names: CXCR4, CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R, Chemokine (C-X-C motif) receptor 4, MYD88, MYD88 Innate Immune Signal Transduction Adaptor, Myeloid Differentiation Primary Response Protein MyD88, Myeloid Differentiation Primary Response Gene (88), Myeloid Differentiation Primary Response 88, Mutant Myeloid Differentiation Primary Response 88, MYD88D
    Entrez ID:
    4615; 7852
    Related biomarkers:
    Expression
    Mutation
    Others
    over1year
    Good teaching case from @BloodJournal Images in #Hematology that (1) not all M-spikes are myeloma, (2) not all lymphoplasmacytic lymphomas are IgM isotype, and (3) remember to request MYD88 and CXCR4 mutations in this setting. #mmsm https://t.co/OpVazjbeNA (@docbraunstein)
    MYD88 (MYD88 Innate Immune Signal Transduction Adaptor) • CXCR4 (Chemokine (C-X-C motif) receptor 4)
    |
    CXCR4 mutation • MYD88 mutation + CXCR4 mutation
    over2years
    Congratulations David and @fdezdelarrea for the excellent study on MYD88 and CXCR4 mutations in IgM MGUS and smoldering WM! Challenge accepted, we will try to improve the sensitivity of #flowcytometry to detect Waldenström's clonal cells! #ASH21 #mmsm (@BrunoPaiva_UNAV)
    MYD88 (MYD88 Innate Immune Signal Transduction Adaptor) • CXCR4 (Chemokine (C-X-C motif) receptor 4)
    |
    CXCR4 mutation • MYD88 mutation + CXCR4 mutation
    over2years
    IgM Plasma Cell Myeloma: Clinicopathologic Features Including Evaluation for MYD88 and CXCR4 Mutations https://t.co/HnYycjhKQj #mmsm #medEd #medtwitter (@Abdallah81MD)
    Clinical
    |
    MYD88 (MYD88 Innate Immune Signal Transduction Adaptor) • CXCR4 (Chemokine (C-X-C motif) receptor 4)
    |
    CXCR4 mutation • MYD88 mutation + CXCR4 mutation