^
    1year
    Thomas Cyberski, medical student @UChicagoMed presents HNSCC patient data showing MYC amplification after chemotherapy and immunotherapy in a poster session at @AACR #AACR23. @AriRosenbergMD @EIzumchenko @UCCancerCenter (@UCCancerCenter)
    Clinical
    |
    MYC (V-myc avian myelocytomatosis viral oncogene homolog)
    |
    MYC amplification
    1year
    Clinical Targeted Next-Generation Panel Sequencing Reveals MYC Amplification Is a Poor Prognostic Factor in Osteosarcoma | JCO Precision Oncology https://t.co/eWd6aIZaAr (@VivekSubbiah)
    Clinical
    |
    MYC (V-myc avian myelocytomatosis viral oncogene homolog)
    |
    MYC amplification
    1year
    SCLC is an aggressive tumor. #MYC amplification is a driver of #SCLC heterogeneity. Extra-chromosomal DNAs bring to proximity enhancers & oncogenes, creating transcription-amplifying units, driving high MYC gene dosage. This can be seen in #liquidbiopsies https://t.co/dHKke78kzO (@jsoriamd)
    Liquid biopsy • Biopsy
    |
    MYC (V-myc avian myelocytomatosis viral oncogene homolog)
    |
    MYC amplification
    2years
    Little is known about tumor-related factors that influence response to #talazoparib in #BreastCancer. Retrospective analysis by Blum et al shows that MYC amplification is associated with shorter overall survival among certain subgroups. https://t.co/qp8JqCBQXn @hoperugo (@CCR_AACR)
    Retrospective data
    |
    MYC (V-myc avian myelocytomatosis viral oncogene homolog)
    |
    MYC amplification
    |
    Talzenna (talazoparib)
    over2years
    Final one on this 🧵: Genomic landscape of human adenosquamous #PancreaticCancer from the same @SU2Cscience @lustgartenfdn team published previously. Note lower frequency of KRAS mutations, Myc amplification in 42%, & unique epigenomic signatures. https://t.co/L5vjvcibR6 (@Aiims1742)
    KRAS (KRAS proto-oncogene GTPase) • MYC (V-myc avian myelocytomatosis viral oncogene homolog)
    |
    KRAS mutation • MYC amplification
    almost4years
    secondary angiosarcoma. cmyc amplification #vasansplz (@vaskannan)
    MYC (V-myc avian myelocytomatosis viral oncogene homolog)
    |
    MYC amplification