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    BIOMARKER:

    MRE11A mutation

    i
    Other names: MRE11A, ATLD, MRE11, MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
    Entrez ID:
    4361
    Related biomarkers:
    Expression
    12ms
    Amazing molecular tumor #MTB board in #GUcsm with @FoundationATCG Two ✌️ interesting cases ➡️ Penile carcinoma 🧬high TMB & BRCA & HER2 amplification....What to do?? By @fedelosco ➡ Prostate cancer 🧬HRR mutation in MRE11A. Does iPARP work?. By me @fundacion_FUCA @IAF_Fleming (@Martin_AngelMD)
    Clinical
    |
    HER-2 (Human epidermal growth factor receptor 2) • TMB (Tumor Mutational Burden) • BRCA (Breast cancer early onset) • MRE11A (MRE11 homolog, double strand break repair nuclease)
    |
    TMB-H • HER-2 amplification • MRE11A mutation