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BIOMARKER:
MDM2 overexpression
i
Other names:
MDM2, HDM2, MGC5370, MDM2 proto-oncogene, E3 ubiquitin protein ligase
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Entrez ID:
4193
Related biomarkers:
Mutation
CNA
Others
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Associations
(3)
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Latest
11ms
The addition of the small molecule imipridone ONC201 to the MDM2-p53 inhibitor milademetan could form a synergistic combination for the treatment of patients with solid tumors with MDM2 overexpression. @ilyassahinMD @UFHealthCancer #oncology #AACR23 https://t.co/eJ7HdTW3QM (@OncLive)
11 months ago
Clinical
|
MDM2 (E3 ubiquitin protein ligase)
|
MDM2 overexpression
|
milademetan (RAIN-32) • dordaviprone (ONC201)
11ms
@ilyassahinMD details the preclinical findings from the study and highlighted how these data could help inform future studies for the treatment of patients with MDM2-overexpressing solid tumors. #oncology #AACR23 https://t.co/atjdGnLsov (@OncLive)
11 months ago
MDM2 (E3 ubiquitin protein ligase)
|
MDM2 overexpression
11ms
Milademetan Plus ONC201 Could Represent Synergistic Combination in MDM2-overexpressing Solid Tumors @ilyassahinMD @UFHealthCancer @AACR #AACR23 #oncology https://t.co/gDZI2QCMZ5 (@OncLive)
11 months ago
MDM2 (E3 ubiquitin protein ligase)
|
MDM2 overexpression
|
milademetan (RAIN-32) • dordaviprone (ONC201)
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