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CANCER:
Liposarcoma
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News alerts, weekly reports and conference planners
Related cancers:
‹
Sarcoma (668
)
Soft Tissue Sarcoma (443
)
Spindle Cell Sarcoma (100
)
Leiomyosarcoma (54
)
Osteosarcoma (54
)
Ewing Sarcoma (45
)
Fibrosarcoma (34
)
Rhabdomyosarcoma (34
)
Uterine Corpus Leiomyosarcoma (23
)
Kaposi Sarcoma (13
)
Neurofibrosarcoma (13
)
Sarcoma (668
)
Soft Tissue Sarcoma (443
)
Spindle Cell Sarcoma (100
)
Leiomyosarcoma (54
)
Osteosarcoma (54
)
Ewing Sarcoma (45
)
Fibrosarcoma (34
)
Rhabdomyosarcoma (34
)
Uterine Corpus Leiomyosarcoma (23
)
Kaposi Sarcoma (13
)
Neurofibrosarcoma (13
)
›
Associations
(25)
News
Trials
Search handles
@JTrentMDPhD
@breelynwilkyMD
@pawel_sobczuk
@schoffski
Search handles
@JTrentMDPhD
@breelynwilkyMD
@pawel_sobczuk
@schoffski
Filter by
Latest
8ms
23 year old female with 5cm myxoid liposarcoma of medial thigh flush against the vagina. Would you consider dose de-escalation to 36Gy given histology? @DianWan13597397 @SprakerMDPhD @jryckman3 (@PhilBlumenfeld)
8 months ago
9ms
lipoblast for liposarcoma (@Rick42877595)
9 months ago
9ms
Liposarcoma. (@FJMazorra)
9 months ago
9ms
Lipoblast for liposarcoma (@PradhanNupur)
9 months ago
9ms
Pleomorphic liposarcoma (@Kingsley2019)
9 months ago
9ms
Myxoid Liposarcoma (@vincenzopolizz7)
9 months ago
9ms
Pleased to welcome Raphael Pollock, MD, PhD @DrRPollock from @OSUCCC_James to present @YaleSurgery Grand Rounds on 'New Directions in Retroperitoneal #Liposarcoma' hosted by @NitaAhujaMD @DrRoyHerbstYale and Dr. Ehud Mendel @YNeurosurgery. @SmilowCancer @YaleMed @YNHH (@YaleCancer)
9 months ago
Grand rounds • Surgery
9ms
Fantastic video, @alegronchi and colleagues, on a standardized right RP #liposarcoma resection approach in @AnnSurgOncol ! I love those CT-image overlays.👍👏👏👏 (@CDV_MD)
9 months ago
Video
9ms
SI on RETROPERITONEAL SARCOMA How to treat liposarcomas located in retroperitoneum @alegronchi @ChirSarcomi_INT @UofTSurgery @UofTSurgOnc @_CSSO @SICOBoard @TARPSWG @ESSOnews @me4_so @juliomayol @AndreasBrandl8 @EYSAC1 @SBonvalot @rutkowskip1972 https://t.co/lCCH0pMCX2 (@ejsotweets)
9 months ago
Surgery
10ms
💙 El passat 8 de juny vam rebre la visita de María Susmozas, fundadora de l'Associació Iker, qui va fer el lliurament de 4.000 € per a investigar el #LiposarcomaMixoide en el Grup Recerca Traslacional que dirigeix @DrCeSarcoma . Moltes gràcies ‼️ https://t.co/Q6GxfaKOEZ (@VHIO)
10 months ago
10ms
Dediff liposarcoma (@IbtissemHamlao2)
10 months ago
10ms
From combination therapies to promising results in myxoid liposarcoma to a study of DNA repair gene in leiomyosarcomas, learn the latest sarcoma research presented by our experts at #ASCO23. https://t.co/jw5t2iBbHk @NeetaSomaiahMD @APConley77 @MNakazawa8 @ASCO #Sarcoma #EndCancer (@MDAndersonNews)
10 months ago
Combination therapy
10ms
Very nice case . my first impresion myxoid liposarcoma ,chordoma ,myxoid chondrosarcoma .. (@alyassri_heba)
10 months ago
10ms
Liposarcoma (@sarikakarthik)
10 months ago
10ms
Atypical lipomatous tumor/ liposarcoma? (@CPremalata)
10 months ago
10ms
Liposarcoma (@karaniwakagotho)
10 months ago
10ms
Liposarcoma (@MahrukhMumtaz9)
10 months ago
10ms
Liposarcoma (@HariharanadhaS)
10 months ago
10ms
Liposarcoma (@JODITAAA)
10 months ago
10ms
Liposarcoma? (@SamanMuhammadA2)
10 months ago
10ms
Pleomorphic liposarcoma (epithelioid type). (@RZitwer)
10 months ago
11ms
@cspramesh My dad is liposarcoma patient he underwent two surgeries back, again recurrence in abdomen region. Need to have the next surgery in TMH please suggest the Dr. for treatment. already visited THM but didn't got positive response..hope you would help me out !!!! (@kundan8831)
11 months ago
Clinical • Surgery
11ms
Following Dr. Robin Jones' talk on #leiomyosarcomas, Dr. Peter Reichardt's talk on #liposarcomas, and Prof. Dr. Bernd Kasper's discussion on #desmoids, @JTrentMDPhD jokes that he has 10 minutes remaining to cover the other 172 subtypes. 😅 #SPAGN2023 (@sarcomapatients)
11 months ago
11ms
Liposarcoma (@Marytresa4)
11 months ago
11ms
myxoid liposarcoma. just got one today 🫡 (@8Nelsonso8)
11 months ago
11ms
Liposarcoma (@remimazorts)
11 months ago
11ms
The oral MDM2/p53 antagonist BI 907828 elicited preliminary antitumor activity and had a manageable safety profile in patients with MDM2-amplified dedifferentiated liposarcoma. @schoffski #scmsm #oncology https://t.co/u9hveeLQyp (@OncLive)
11 months ago
Clinical
|
MDM2 (E3 ubiquitin protein ligase)
|
brigimadlin (BI 907828)
12ms
The oral MDM2/p53 antagonist BI 907828 elicited preliminary antitumor activity and had a manageable safety profile in patients with MDM2-amplified dedifferentiated liposarcoma. @schoffski #scmsm #oncology https://t.co/lxZOMppl50 (@OncLive)
12 months ago
Clinical
|
MDM2 (E3 ubiquitin protein ligase)
|
brigimadlin (BI 907828)
12ms
BI 907828 Demonstrates Early Efficacy, Safety in MDM2-amplified Dedifferentiated Liposarcoma @schoffski #scmsm #oncology https://t.co/3ogNSnm8e6 (@OncLive)
12 months ago
Clinical
|
MDM2 (E3 ubiquitin protein ligase)
|
brigimadlin (BI 907828)
1year
Atypical lipomatous tumor. MDM2 and CDK4 (@NishthaAhuja7)
1 year ago
CDK4 (Cyclin-dependent kinase 4)
over1year
Atypical lipomatous tumor , MDM2 + , CD34- , ring chromosomes present (@RekhaSi99160584)
over 1 year ago
CD34 (CD34 molecule)
over1year
Dedifferentiated liposarcoma, MDM2, CDK4, P16 (@NewjobiRakesh)
over 1 year ago
CDK4 (Cyclin-dependent kinase 4)
over1year
FISH positive for DDIT3 and history of previous Myxoid Liposarcoma!! 🥹✨🤩🔬💟 (@tlabiano)
over 1 year ago
DDIT3 (DNA-damage-inducible transcript 3)
almost2years
MDM2 amplification is a clinically actionable target, occurs in most cancer types, with highest rates in sarcoma, bladder, biliary, lung, upper GI, breast cancer, melanoma. Across tumor types the frequency is 1.2%. Virtually all well-/dedifferentiated liposarcomas are amplified. (@schoffski)
almost 2 years ago
Clinical
|
MDM2 (E3 ubiquitin protein ligase)
|
MDM2 amplification
almost2years
Sandra D’Angelo presenting NYEso1 cellular therapy against myxoid #liposarcoma #asco22. 40% and mPFS 8.7 months (@JTrentMDPhD)
almost 2 years ago
CTAG1B (Cancer/testis antigen 1B)
almost2years
#ASCO22 11500 - @sandrapdangelo @MSKCancerCenter study on #Immunotherapy for myxoid/round cell liposarcoma #sarcoma pts by anti-NY-ESO-1 #TCR autologous #Tcell (lete-cel @GSK). Up to 40% of pts responded for median 7.5m. How can we boost responses?Vaccination? Cytokines? (@drmcopeman)
almost 2 years ago
Clinical
|
CTAG1B (Cancer/testis antigen 1B)
|
letetresgene autoleucel (GSK3377794)
2years
A Phase 1/2 Open-label Study Investigating Safety, Tolerability & Efficacy of ASP0739 as Single Agent and in Combination with Pembrolizumab in Pts with Tumors known to Express NY-ESO-1 #Synovial #Sarcoma #Myxoid #Liposarcoma https://t.co/KrGVAQVkjG (@JTrentMDPhD)
2 years ago
Clinical • Combination therapy
|
CTAG1B (Cancer/testis antigen 1B)
|
CTAG1B expression
|
Keytruda (pembrolizumab) • ASP0739
over2years
I now have two MDM2 inhibitors available in ongoing clinical trials in Leuven for patients with advanced dedifferentiated liposarcoma and select other mesenchymal and epithelial tumours with MDM2 amplification. Get in touch in case you have potential candidates! (@schoffski)
over 2 years ago
Clinical
|
MDM2 (E3 ubiquitin protein ligase)
|
MDM2 amplification
over2years
🚨Very promissing results of letetresgene autoleucel in advanced myxoid/round cell liposarcoma (NY-ESO-1 positive) 🌟durable response 🌟ORR 40% DCR 90% ☠️Tocitity: cytokine release syndrome (30% G3) @sandrapdangelo @MSKSarcoma #CTOS2021 @ctosociety @OncoAlert #sarcoma (@pawel_sobczuk)
over 2 years ago
CTAG1B (Cancer/testis antigen 1B)
|
letetresgene autoleucel (GSK3377794)
over2years
Genomic instability focused around brachyura gene in #chordoma. MYC in #osteosarcoma. MDM2 in #liposarcoma #ChildhoodCancer #CTOS2021 #sarcoma @ctosociety (@JTrentMDPhD)
over 2 years ago
MDM2 (E3 ubiquitin protein ligase)
over2years
Work up for DDif liposarcoma, Any history of amputation (osteosarcoma), CD25, CD68, CD1a, CD163 (Histiocytic/Dendritic differentiation) EBER-ISH for ebv sm associated tumor (very unlikely), ALK-1, and NTRK fusion? (@IbrahimMDpatho)
over 2 years ago
IL2RA (Interleukin 2 receptor, alpha) • CD163 (CD163 Molecule) • CD68 (CD68 Molecule) • NTRK (Neurotrophic receptor tyrosine kinase)
|
NTRK fusion
over2years
Yes indeed they are in the same spectrum. spindle cell/pleomorphic lipoma, atypical spindle cell/pleomorphic lipomatous tumor, pleomorphic liposarcoma, myofibroblastoma, cellular angiofibroma, and acral fibromyxoma show loss of RB1 protein. PMID: 33802620 (@EssaoudiMohamed)
over 2 years ago
RB1 (RB Transcriptional Corepressor 1)
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