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BIOMARKER:
KRAS G12S
i
Other names:
KRAS, KRAS1, KRAS2, Kirsten rat sarcoma viral oncogene homolog
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Entrez ID:
3845
Related biomarkers:
Expression
Mutation
CNA
Others
‹
STK11 deletion + KRAS mutation (6)
KRAS G12C + PD-L1 overexpression (4)
KRAS mutation + PD-L1 expression (4)
CPS1 overexpression + KRAS mutation + STK11 mutation (3)
HER-2 amplification + KRAS G12D (3)
KEAP1 deletion + KRAS mutation (3)
PD-L1 overexpression + KRAS mutation (3)
EGFR exon 19 deletion + KRAS mutation (2)
KRAS G12C + PD-L1 underexpression (2)
KRAS mutation + PD-L1 negative (2)
MSI-L/dMMR + KRAS G12V (2)
AXL overexpression + KRAS G12C (1)
CDH2 overexpression + KRAS wild-type (1)
Chr t(11;14) + KRAS mutation (1)
EGFR C797S + KRAS amplification + RB1 deletion (1)
EGFR L858R + KRAS amplification + RB1 deletion (1)
EGFR T790M + KRAS amplification + RB1 deletion (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
EGFR exon 19 deletion + TP53 mutation + CDK6 amplification + KRAS amplification (1)
EGFR expression + KRAS G12C (1)
EGFR overexpression + KRAS 13D (1)
EGFR overexpression + KRAS mutation (1)
FGFR1 overexpression + KRAS G12C (1)
GNA13 deletion + KRAS mutation (1)
GOPC-ROS1 fusion + KRAS Q61H (1)
HER-2 amplification + KRAS exon 2 wild-type (1)
HER-2 amplification + KRAS wild-type (1)
HER-2 overexpression + KRAS wild-type (1)
IGF1R overexpression + KRAS mutation (1)
IR overexpression + KRAS mutation (1)
IRS2 amplification + KRAS mutation (1)
KEAP1 mutation + KRAS wild-type (1)
KRAS A146 + TMB-H (1)
KRAS G12C + PD-L1 expression (1)
KRAS G12C + PD-L1 underexpression + STK11 mutation (1)
KRAS G12D + Chr del(9)(p21) (1)
KRAS G12D + HER-2 amplification + TMB-H (1)
KRAS G12D + TP53 deletion (1)
KRAS amplification + BRAF wild-type (1)
KRAS amplification + RAS wild-type (1)
KRAS mutation + PTPN11 overexpression + PD-L1 overexpression (1)
KRAS mutation + BCL2A1 overexpression (1)
KRAS mutation + CDK9 overexpression + HR positive (1)
KRAS mutation + EGFR amplification (1)
KRAS mutation + ER expression (1)
KRAS mutation + HER-2 positive (1)
KRAS mutation + HR positive (1)
KRAS mutation + PD-L1 underexpression (1)
KRAS mutation + PIK3CA wild-type (1)
KRAS mutation + PTPN11 overexpression (1)
KRAS mutation + TP53 mutation + GNA13 deletion (1)
KRAS mutation + TP53 mutation + PD-L1 expression + PD-1 expression (1)
KRAS mutation + YKL-40 overexpression (1)
KRAS wild-type + BRAF V600E (1)
KRAS wild-type + NRAS wild-type + MSI-H/dMMR (1)
KRAS mutation + STK11 mutation + AXL expression (1)
MLL-AFF1 fusion + KRAS mutation (1)
MSI-H/dMMR + KRAS G12D (1)
MSI-H/dMMR + KRAS Mutation (1)
MSI-H/dMMR + KRAS wild-type + BRAF wild-type (1)
MTAP deletion + KRAS G12C (1)
PD-L1 negative + KRAS G12C (1)
PD-L1 overexpression + KRAS G12C + TP53 mutation (1)
POMK-NRG1 fusion + KRAS mutation (1)
POMK‐NRG1 fusion + KRAS G12D (1)
PTEN deletion + KRAS G12C (1)
RET positive + KRAS G12V (1)
ROS1 fusion + KRAS G12C (1)
STK11 mutation + KRAS mutation + TP53 deletion (1)
STRN-ALK fusion + KRAS G13D (1)
TP53 S12F + KRAS G12D + TMB-L (1)
HER-2 amplification + KRAS G12C (0)
PRMT5 overexpression + KRAS mutation (0)
STK11 deletion + KRAS mutation (6)
KRAS G12C + PD-L1 overexpression (4)
KRAS mutation + PD-L1 expression (4)
CPS1 overexpression + KRAS mutation + STK11 mutation (3)
HER-2 amplification + KRAS G12D (3)
KEAP1 deletion + KRAS mutation (3)
PD-L1 overexpression + KRAS mutation (3)
EGFR exon 19 deletion + KRAS mutation (2)
KRAS G12C + PD-L1 underexpression (2)
KRAS mutation + PD-L1 negative (2)
MSI-L/dMMR + KRAS G12V (2)
AXL overexpression + KRAS G12C (1)
CDH2 overexpression + KRAS wild-type (1)
Chr t(11;14) + KRAS mutation (1)
EGFR C797S + KRAS amplification + RB1 deletion (1)
EGFR L858R + KRAS amplification + RB1 deletion (1)
EGFR T790M + KRAS amplification + RB1 deletion (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
EGFR exon 19 deletion + TP53 mutation + CDK6 amplification + KRAS amplification (1)
EGFR expression + KRAS G12C (1)
EGFR overexpression + KRAS 13D (1)
EGFR overexpression + KRAS mutation (1)
FGFR1 overexpression + KRAS G12C (1)
GNA13 deletion + KRAS mutation (1)
GOPC-ROS1 fusion + KRAS Q61H (1)
HER-2 amplification + KRAS exon 2 wild-type (1)
HER-2 amplification + KRAS wild-type (1)
HER-2 overexpression + KRAS wild-type (1)
IGF1R overexpression + KRAS mutation (1)
IR overexpression + KRAS mutation (1)
IRS2 amplification + KRAS mutation (1)
KEAP1 mutation + KRAS wild-type (1)
KRAS A146 + TMB-H (1)
KRAS G12C + PD-L1 expression (1)
KRAS G12C + PD-L1 underexpression + STK11 mutation (1)
KRAS G12D + Chr del(9)(p21) (1)
KRAS G12D + HER-2 amplification + TMB-H (1)
KRAS G12D + TP53 deletion (1)
KRAS amplification + BRAF wild-type (1)
KRAS amplification + RAS wild-type (1)
KRAS mutation + PTPN11 overexpression + PD-L1 overexpression (1)
KRAS mutation + BCL2A1 overexpression (1)
KRAS mutation + CDK9 overexpression + HR positive (1)
KRAS mutation + EGFR amplification (1)
KRAS mutation + ER expression (1)
KRAS mutation + HER-2 positive (1)
KRAS mutation + HR positive (1)
KRAS mutation + PD-L1 underexpression (1)
KRAS mutation + PIK3CA wild-type (1)
KRAS mutation + PTPN11 overexpression (1)
KRAS mutation + TP53 mutation + GNA13 deletion (1)
KRAS mutation + TP53 mutation + PD-L1 expression + PD-1 expression (1)
KRAS mutation + YKL-40 overexpression (1)
KRAS wild-type + BRAF V600E (1)
KRAS wild-type + NRAS wild-type + MSI-H/dMMR (1)
KRAS mutation + STK11 mutation + AXL expression (1)
MLL-AFF1 fusion + KRAS mutation (1)
MSI-H/dMMR + KRAS G12D (1)
MSI-H/dMMR + KRAS Mutation (1)
MSI-H/dMMR + KRAS wild-type + BRAF wild-type (1)
MTAP deletion + KRAS G12C (1)
PD-L1 negative + KRAS G12C (1)
PD-L1 overexpression + KRAS G12C + TP53 mutation (1)
POMK-NRG1 fusion + KRAS mutation (1)
POMK‐NRG1 fusion + KRAS G12D (1)
PTEN deletion + KRAS G12C (1)
RET positive + KRAS G12V (1)
ROS1 fusion + KRAS G12C (1)
STK11 mutation + KRAS mutation + TP53 deletion (1)
STRN-ALK fusion + KRAS G13D (1)
TP53 S12F + KRAS G12D + TMB-L (1)
HER-2 amplification + KRAS G12C (0)
PRMT5 overexpression + KRAS mutation (0)
›
Related tests:
therascreen® KRAS RGQ PCR Kit (5)
therascreen® KRAS RGQ PCR Kit (5)
Associations
(9)
News
Trials
Search handles
@pashtoonkasi
Search handles
@pashtoonkasi
Filter by
Latest
1year
A 12-11 One more trial!! Pan #RAS G12i Ph I/Ib 📌https://t.co/xNGnaEYbli 📌n=141 📌RMC6326 📌For KRAS G12A/G12D/ G12R/ G12S or G12V mutant #CRC & other solid tumors 📌Primary end points: DLT, Safety 📌Trial open in the US https://t.co/2y2vpJDmAH #CRCTrialsChat #CRCSM (@manjuggm)
1 year ago
Clinical
|
KRAS (KRAS proto-oncogene GTPase) • RAS (Rat Sarcoma Virus)
|
KRAS G12D • KRAS G12V • KRAS G12A • KRAS G12 • KRAS G12S
2years
What’s #KRAS next? #G12S @kevansf @UCSFCancer #AACR22 #CRC #Squamous #LungCancer #Rectal #CRC (@KRASKickers)
2 years ago
KRAS (KRAS proto-oncogene GTPase)
|
KRAS G12 • KRAS G12S
3years
🙌🏾 to open at @IntMedatIowa few days. While #pancreascancer #PANCSM is the major cohort, the vaccine 💉 is for multiple KRAS mutations. So #lcsm #HPBCSM #cholangiocarcinoma #CRCSM and I believe #ovariancancer. Using the #ctDNA @NateraOncology. G12D G12R G12V G12A G12C G12S G13D (@pashtoonkasi)
3 years ago
Circulating tumor DNA
|
KRAS (KRAS proto-oncogene GTPase)
|
KRAS mutation • KRAS G12D • KRAS G12V • KRAS G12A • KRAS G12S
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