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BIOMARKER:
KIT expression
i
Other names:
KIT, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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Entrez ID:
3815
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
KIT mutation (32)
KIT exon 11 mutation (13)
KIT exon 9 mutation (9)
KIT N822K (7)
KIT D816V (6)
KIT exon 13 mutation (6)
KIT exon 17 mutation (6)
KIT L576P (5)
KIT T670I (4)
KIT D820Y (3)
KIT K642E (3)
KIT V559D (3)
KIT V654A (3)
KIT wild-type (3)
KIT S628N (2)
KIT W557_V559delinsF (2)
KIT exon 11 mutation + KIT exon 17 mutation (2)
KIT exon 18 mutation (2)
KIT exon 8 mutation (2)
BRAF G466V + KIT K509Q (1)
KDR Q472H + KIT M541L (1)
KIT A829P (1)
KIT D816G (1)
KIT D816H (1)
KIT D818Y (1)
KIT D820A (1)
KIT D820G (1)
KIT L576 (1)
KIT M541L (1)
KIT M552_V555delMYEV (1)
KIT N820Y (1)
KIT N822Y (1)
KIT V559A + KIT N822I (1)
KIT V559_E561del (1)
KIT V560E (1)
KIT V560G (1)
KIT W557_V559>C (1)
KIT W557_V559>F (1)
KIT Y823D (1)
KIT exon 11 W557_K558delins (1)
KIT exon 14 mutation (1)
KIT exon 17 mutation + KIT exon 18 mutation (1)
KIT translocation (1)
NR4A3 rearrangement + KIT mutation (1)
KIT D820E (0)
KIT K509Q (0)
KIT N822I (0)
KIT V559 (0)
KIT V559A (0)
KIT V560D (0)
KIT W557 (0)
KIT rs3733542 (0)
KIT mutation (32)
KIT exon 11 mutation (13)
KIT exon 9 mutation (9)
KIT N822K (7)
KIT D816V (6)
KIT exon 13 mutation (6)
KIT exon 17 mutation (6)
KIT L576P (5)
KIT T670I (4)
KIT D820Y (3)
KIT K642E (3)
KIT V559D (3)
KIT V654A (3)
KIT wild-type (3)
KIT S628N (2)
KIT W557_V559delinsF (2)
KIT exon 11 mutation + KIT exon 17 mutation (2)
KIT exon 18 mutation (2)
KIT exon 8 mutation (2)
BRAF G466V + KIT K509Q (1)
KDR Q472H + KIT M541L (1)
KIT A829P (1)
KIT D816G (1)
KIT D816H (1)
KIT D818Y (1)
KIT D820A (1)
KIT D820G (1)
KIT L576 (1)
KIT M541L (1)
KIT M552_V555delMYEV (1)
KIT N820Y (1)
KIT N822Y (1)
KIT V559A + KIT N822I (1)
KIT V559_E561del (1)
KIT V560E (1)
KIT V560G (1)
KIT W557_V559>C (1)
KIT W557_V559>F (1)
KIT Y823D (1)
KIT exon 11 W557_K558delins (1)
KIT exon 14 mutation (1)
KIT exon 17 mutation + KIT exon 18 mutation (1)
KIT translocation (1)
NR4A3 rearrangement + KIT mutation (1)
KIT D820E (0)
KIT K509Q (0)
KIT N822I (0)
KIT V559 (0)
KIT V559A (0)
KIT V560D (0)
KIT W557 (0)
KIT rs3733542 (0)
›
Related tests:
Dako c-KIT pharmDx (1)
Dako c-KIT pharmDx (1)
Associations
(4)
News
Trials
Search handles
@AlkaliDr
Search handles
@AlkaliDr
Filter by
Latest
1year
Yes, exactly, this is why CD117 expression does not confirm leukemia (@SibaElHussein)
1 year ago
KIT (KIT proto-oncogene, receptor tyrosine kinase)
|
KIT expression
1year
Our #DATA trial now online. Best benefit was seen in transplanted pts A phase II study of combination daunorubicin, cytarabine (Ara‐c), and nilotinib (TAsigna) (DATA) in patients newly diagnosed with acute myeloid leukemia with KIT expression https://t.co/x9mqmuexJ5 (@AlkaliDr)
1 year ago
Clinical
|
KIT (KIT proto-oncogene, receptor tyrosine kinase)
|
KIT expression
|
Tasigna (nilotinib) • daunorubicin • Vyxeos (cytarabine/daunorubicin liposomal formulation)
over1year
Our prospective trial is out @AjHematology. DATA regimen in #AML A Phase II Study of Combination Daunorubicin, Cytarabine (Ara-c) and Nilotinib (TAsigna) (DATA) in Patients Newly Diagnosed with Acute Myeloid Leukemia with KIT Expression https://t.co/DMufqKBTuz (@AlkaliDr)
over 1 year ago
Clinical
|
KIT (KIT proto-oncogene, receptor tyrosine kinase)
|
KIT expression
|
Tasigna (nilotinib) • daunorubicin • Vyxeos (cytarabine/daunorubicin liposomal formulation)
3years
@sanamloghavi this is likely a naive question but do you think that the PL cells with abnormal CD123/CD117 expression are a specific feature of post-remission CH or that they may also be present in CH that has not (yet) produced leukemia? (@juliamaxson)
3 years ago
Clinical
|
KIT (KIT proto-oncogene, receptor tyrosine kinase) • CD123 (Interleukin 3 Receptor Subunit Alpha)
|
KIT expression
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