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    BIOMARKER:

    IKZF1 mutation

    i
    Other names: IKZF1, IKAROS Family Zinc Finger 1, Zinc Finger Protein Subfamily 1A 1 (Ikaros), Protein Phosphatase 1 Regulatory Subunit 92, Ikaros Family Zinc Finger Protein 1, Lymphoid Transcription Factor LyF-1, DNA-Binding Protein Ikaros, ZNFN1A1, IKAROS, LYF1, IK1, IKAROS Family Zinc Finger 1 (Ikaros), CLL-Associated Antigen KW-6, Hs.54452, PPP1R92, PRO0758, CVID13, LyF-1
    Entrez ID:
    10320
    Related biomarkers:
    Expression
    Mutation
    CNA
    almost2years
    #EHA22 #leusm Stanulla: Germline mutations in IKZF1, ETV6, RUNX1, and PAX5 are rare causes of ALL, but may be under-recognized. Use of standardized cancer susceptibility and immune dysfunction questionnaire at patient initial evaluation is a nice idea. (@hemedoc)
    Clinical
    |
    RUNX1 (RUNX Family Transcription Factor 1) • ETV6 (ETS Variant Transcription Factor 6) • IKZF1 (IKAROS Family Zinc Finger 1) • PAX5 (Paired Box 5)
    |
    IKZF1 mutation