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BIOMARKER:
IDH1 R132H
i
Other names:
HEL-216, HEL-S-26, Epididymis Luminal Protein 216, Isocitrate Dehydrogenase 1 (NADP+), Epididymis Secretory Protein Li 26, IDH1, Isocitrate Dehydrogenase (NADP(+)) 1, Isocitrate Dehydrogenase 1 (NADP+), Soluble
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Entrez ID:
3417
Related biomarkers:
Expression
Mutation
Others
‹
IDH1 mutation (79)
IDH1 R132C (5)
IDH wild-type (3)
IDH1 R132 (3)
FLT3-ITD mutation + IDH1 mutation (2)
IDH1 R132G (2)
IDH1 wild-type + BRAF mutation (2)
IDH1 wild-type + NF1 mutation (2)
DNMT3A mutation + IDH mutation (1)
EGFR L858R + IDH1 R132C (1)
EGFR mutation + IDH1 mutation (1)
EGFR mutation+ IDH1 R132H (1)
FLT3 mutation + IDH1 mutation (1)
IDH1 R132C + EGFR L861Q (1)
IDH1 R132C + IDH1 S280F (1)
IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)
IDH1 R132H + PTEN C78T (1)
IDH1 R132L (1)
IDH1 R132S (1)
IDH1 R132V (1)
IDH1 mutation + TP53 mutation (1)
IDH1 rs1437410 (1)
IDH1 mutation (79)
IDH1 R132C (5)
IDH wild-type (3)
IDH1 R132 (3)
FLT3-ITD mutation + IDH1 mutation (2)
IDH1 R132G (2)
IDH1 wild-type + BRAF mutation (2)
IDH1 wild-type + NF1 mutation (2)
DNMT3A mutation + IDH mutation (1)
EGFR L858R + IDH1 R132C (1)
EGFR mutation + IDH1 mutation (1)
EGFR mutation+ IDH1 R132H (1)
FLT3 mutation + IDH1 mutation (1)
IDH1 R132C + EGFR L861Q (1)
IDH1 R132C + IDH1 S280F (1)
IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)
IDH1 R132H + PTEN C78T (1)
IDH1 R132L (1)
IDH1 R132S (1)
IDH1 R132V (1)
IDH1 mutation + TP53 mutation (1)
IDH1 rs1437410 (1)
›
Related tests:
Abbott RealTime IDH1 (4)
Abbott RealTime IDH1 (4)
Associations
(9)
News
Trials
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Latest
over1year
Glioma w/ microvascular proliferation. To confirm GBM, IDHwt status must be proven. Negative IHC for IDH1 R132H may be sufficient given age>55. Instead, if IDHmut, Dx is either Astro or Oligo grade 4 depending on 1p19q. Pediatric-type HGGs such as H3K27M unlikely given the age. (@FraSanvito)
over 1 year ago
Clinical
|
IDH1 (Isocitrate dehydrogenase (NADP(+)) 1)
|
IDH1 R132H • IDH wild-type • IDH1 R132
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