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BIOMARKER:
HR negative
i
Other names:
ESR1, Era, ESR, NR3A1, ER, ER beta, PGR, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3, NR3C3
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Entrez ID:
2099
;
5241
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ER mutation (18)
ER Y537S (17)
ER D538G (11)
ESR1 mutation (9)
ER positive + ESR1 mutation (6)
ER Y537N (5)
ER negative + PIK3CA H1047R (2)
PIK3CA mutation + ESR1 mutation (2)
ER D538G + ER F404L (1)
ER E380Q (1)
ER E380Q + ER F404L (1)
ER F404L (1)
ER L536Q (1)
ER T594T (1)
ER Y537C (1)
ER rs2234693 (1)
ESR1 rs1801132 (1)
ESR1 rs2228480 (1)
ESR1 rs2234693T>C (1)
ESR1 rs9322354 (1)
HR positive + PIK3CA H1047R (1)
HR positive + PIK3CA H1047R + ER D538G (1)
HR positive + PIK3CA H1047R + PIK3CA D350G + ER D538G (1)
PIK3CA H1047R + PIK3CA D959N + ER E380Q (1)
PIK3CA mutation + ER mutation (1)
ER mutation (18)
ER Y537S (17)
ER D538G (11)
ESR1 mutation (9)
ER positive + ESR1 mutation (6)
ER Y537N (5)
ER negative + PIK3CA H1047R (2)
PIK3CA mutation + ESR1 mutation (2)
ER D538G + ER F404L (1)
ER E380Q (1)
ER E380Q + ER F404L (1)
ER F404L (1)
ER L536Q (1)
ER T594T (1)
ER Y537C (1)
ER rs2234693 (1)
ESR1 rs1801132 (1)
ESR1 rs2228480 (1)
ESR1 rs2234693T>C (1)
ESR1 rs9322354 (1)
HR positive + PIK3CA H1047R (1)
HR positive + PIK3CA H1047R + ER D538G (1)
HR positive + PIK3CA H1047R + PIK3CA D350G + ER D538G (1)
PIK3CA H1047R + PIK3CA D959N + ER E380Q (1)
PIK3CA mutation + ER mutation (1)
›
Associations
(25)
News
Trials
Search handles
@Dr_Ivanoncologo
Search handles
@Dr_Ivanoncologo
Filter by
Latest
over2years
While #pathologic complete response rates were numerically higher in the PGM treatment arm for hormone receptor-negative, #HER2-negative #breastcancer (32% versus 21%), this small increase did not meet I-SPY’s prespecified threshold for graduation🤔📑 (@Dr_Ivanoncologo)
over 2 years ago
Clinical
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative • HR negative
over2years
ASCO Guideline Update: Chemo- and Targeted Therapy for Patients With HER2-Negative Metastatic #BreastCancer That is Either Endocrine-Pretreated or Hormone Receptor-Negative https://t.co/rdKpSF6ymD #JCO #BCSM @BeverlyMoy @DrLisaCarey (@ASCO_pubs)
over 2 years ago
Clinical
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative • HR negative
over3years
What? We use neoadjuvant chemotherapy in breast cancer all the time. I can find, with little effort, scads of articles showing its benefit, especially in hormone receptor negative and HER2+ cancer.🤦🏻♂️ (@gorskon)
over 3 years ago
Clinical
|
HER-2 (Human epidermal growth factor receptor 2)
|
HR negative
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