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    DRUG:

    Fyarro (nanoparticle albumin-bound rapamycin)

    i
    Other names: ABI-009, nab-rapamycin, nab-sirolimus, EOC009
    Company:
    Aadi Biosci, EOC Pharma
    Drug class:
    mTORC1 inhibitor
    Related drugs:
    1year
    We report on 2 cases of exceptional response to combination gemcitabine+sirolimus after failure of nab-sirolimus and gemcitabine mono in TSC-mutated #sarcoma ↪️Molecular rationale support combination of these drugs! @MDAndersonNews @NeetaSomaiahMD https://t.co/rlbr0c1lqM (@NassifElise)
    Clinical
    |
    TSC1 (TSC complex subunit 1)
    |
    TSC1 mutation
    |
    gemcitabine • Fyarro (nanoparticle albumin-bound rapamycin)
    1year
    Investigators Unpack Role of Nab-Sirolimus for Solid Tumors With TSC1/2 Mutations @schulte_md @AgulnikMd @ucsfhealth @cityofhope #scmsm #oncology https://t.co/uIs7mnKbiz (@OncLiveSOSS)
    TSC1 (TSC complex subunit 1)
    |
    TSC1 mutation
    |
    Fyarro (nanoparticle albumin-bound rapamycin)